ID   A0A3P8NFG2_ASTCA        Unreviewed;       765 AA.
AC   A0A3P8NFG2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Myotubularin related protein 10 {ECO:0000313|Ensembl:ENSACLP00000003525.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000003525.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000003525.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000003525.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR   AlphaFoldDB; A0A3P8NFG2; -.
DR   STRING; 8154.ENSACLP00000003525; -.
DR   Ensembl; ENSACLT00000003605.1; ENSACLP00000003525.1; ENSACLG00000002373.1.
DR   GeneTree; ENSGT00940000156900; -.
DR   OMA; APHQLYD; -.
DR   OrthoDB; 5474662at2759; -.
DR   Proteomes; UP000265100; Chromosome 1.
DR   Bgee; ENSACLG00000002373; Expressed in anal fin and 8 other cell types or tissues.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR022587; MTMR12-like_C.
DR   InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR   InterPro; IPR030564; Myotubularin_fam.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR   PANTHER; PTHR10807:SF39; MYOTUBULARIN-RELATED PROTEIN 10; 1.
DR   Pfam; PF12578; 3-PAP; 1.
DR   Pfam; PF06602; Myotub-related; 2.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE   3: Inferred from homology;
FT   DOMAIN          205..644
FT                   /note="Myotubularin phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51339"
FT   REGION          682..727
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   765 AA;  87397 MW;  4A0D7C8B715DDF71 CRC64;
     MFPAKVTKPT FKCYLPPAQT DVKNTVEKPL KKLEAKLLSG EIVVNEVNFV RKCISTENNQ
     EGLWGKLICT NFKVSFIPQD TSPKQKSTLS HLLLGEHDIP LTCLEQVVTV NDTKGKKKVL
     GSNQKLKFNP TELILYCKDL RMIRFCFEEA GPESARKVCL AIAHYSHPAD LQLLFGFEYQ
     GRRYHESKEE RVNGSTPRGL QTPIFDRSSD WDREIKRTNA SEWRVCSINQ SYTVSSSLPE
     HIVVPSSLTD QDLMQYASSF TDRRIPMWCW SHSNGSALVR MASLTDPLQL KKTEQKIFAA
     ITKSHPQRNE PFRSDLDKSL PSILDIQSAF VKLRQICILD PFEESEERWL STIENSRWLE
     YVRAFLKHSA EMVYHLEGGN SSVILQEEED RDLNCVVSAL MQLMLDPRYR SLIGFQSLVQ
     KEWVMAGHRF LDRCNHLKKN DKEESPLFLL FLDCVWQIMN QYPAAFEFTE TYLTVLSDSM
     WIPLFSTFLF SSSKQRAQHL MDFAKHKAIP QGEDQVVYFP PVWEWSQQFS TKDQTLFNNP
     MYVGKGAACV QNGEVKTFKR KQKAYSSTLR GTPTNLRNGV KGGEESLTRR SSLANELKSE
     LTPVKDLSPS ERFFKDWFSR PADLQGLLIP LLMPSHMAFW KLFFLRWVPE ACISKGGPVT
     TYHKLSQLVD EIEILQSQLR QYKGTSPGNT PLTSSGGNPT DQRRMYFQAS SPDDPSTPPE
     CLTSSFPFTP TGNLSRRTVQ GTPISKFLNG ARIWLSTETL ANDTV
//