ID A0A3P8NID2_ASTCA Unreviewed; 647 AA.
AC A0A3P8NID2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Atrial natriuretic peptide-converting enzyme-like {ECO:0000313|Ensembl:ENSACLP00000004519.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000004519.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000004519.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000004519.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00090}.
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DR AlphaFoldDB; A0A3P8NID2; -.
DR STRING; 8154.ENSACLP00000004519; -.
DR Ensembl; ENSACLT00000004612.1; ENSACLP00000004519.1; ENSACLG00000003036.1.
DR GeneTree; ENSGT00940000166686; -.
DR OMA; TESCEQY; -.
DR OrthoDB; 5483535at2759; -.
DR Proteomes; UP000265100; Chromosome 11.
DR Bgee; ENSACLG00000003036; Expressed in anal fin and 2 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd07066; CRD_FZ; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 4.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR015526; Frizzled/SFRP.
DR InterPro; IPR020067; Frizzled_dom.
DR InterPro; IPR036790; Frizzled_dom_sf.
DR PANTHER; PTHR11309; FRIZZLED; 1.
DR Pfam; PF01392; Fz; 4.
DR SMART; SM00063; FRI; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 4.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50038; FZ; 4.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00090}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..647
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017946420"
FT DOMAIN 22..131
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DOMAIN 140..267
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DOMAIN 259..382
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DOMAIN 374..488
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DISULFID 65..103
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 96..120
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 216..240
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 335..359
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 379..440
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 387..433
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 453..477
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
SQ SEQUENCE 647 AA; 72090 MW; F1D51754BD984FC2 CRC64;
MKHLFLAVLG LLSLQWVHSR SDDRTNCKPF TASFCQGVGY TTTLHPTGVQ GYNLQQIGQI
VETACSPHVA KLMCRIVVPE CSSEDDSRLK PCRALCVQVK ADCESTLRAK WLSWPLRLRC
ETLPESNCVG ASSVVSVIQT PPSACQPITV PFCKDTTYTE TVLPGQETQD NIALTINRFN
PLVTSGCSPH LKPFLCSVYV PECVSGKPRP PCRTLCEHAR SHCGAQMRSL SLEWPEALKC
EAFTTESCEH VPVISVSQAP SAACQPITVP LCKDLHYTET VLPEKETQDV ISLKINQFYP
LVKVECSSHL KPLLCSIFVP ECVSGKPRPP CRTLCEKAKS GCEPLMNKFG IPWPEELKCT
AFTTESCEHY GVSSSGGVCE PITIPMCQGL SYNQTLIPNL LGHTSQREAF TKMSFFNSMV
QTVCSVDIRI FLCRVYAPQC EAGQAQWPCR SFCEKARRDC EGLMSNFGIS WPEELQCSSF
PEEMCISEEK RSKMLNAEDV AAKLEAGGYS VHGKALTLST ARLLLTLMDA DQSGDLDVVE
FFKLERFVGA IRREYVESYG SRNQPSVTEN QMKKALVARE FHLDDETFRV LWQEYRSEGG
INYDKYVAAL AKLQILKDRF KAHLLNLPCD CQVASFTMNQ FMKTAIV
//
