ID A0A3P8NJY2_ASTCA Unreviewed; 203 AA.
AC A0A3P8NJY2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Peflin {ECO:0000256|ARBA:ARBA00041025};
DE AltName: Full=PEF protein with a long N-terminal hydrophobic domain {ECO:0000256|ARBA:ARBA00041490};
DE AltName: Full=Penta-EF hand domain-containing protein 1 {ECO:0000256|ARBA:ARBA00042606};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000005116.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000005116.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000005116.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00037873}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00037873}.
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DR AlphaFoldDB; A0A3P8NJY2; -.
DR STRING; 8154.ENSACLP00000005116; -.
DR Ensembl; ENSACLT00000005222.1; ENSACLP00000005116.1; ENSACLG00000003443.1.
DR GeneTree; ENSGT00940000155722; -.
DR OMA; QFIVTCI; -.
DR Proteomes; UP000265100; Chromosome 22.
DR Bgee; ENSACLG00000003443; Expressed in ovary and 8 other cell types or tissues.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048306; F:calcium-dependent protein binding; IEA:UniProt.
DR CDD; cd16184; EFh_PEF_peflin; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR46212; PEFLIN; 1.
DR PANTHER; PTHR46212:SF3; PEFLIN; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..203
FT /note="Peflin"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017979389"
FT DOMAIN 33..68
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 100..135
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 203 AA; 23451 MW; DA43D74D17EC040C CRC64;
MGIFKVSQNA FLSFSVSLPH LFFCLCVGNI PPGVNPEAYQ WFQSVDTDRS GFINLKELKQ
ALVNSNWSSF NDETCLMMIN MFDKTRSGRM DLFGFSALWD FMQRWRAMFQ QYDRDRSGCI
SGMELQQALA QMGYNLSPQF SETLVQRFTV RGARPGIQLD RFIHVCTQLQ SMTQVFRERD
TSMTGNIRLS YEDFLSSAVT RLM
//
