ID A0A3P8NLL5_ASTCA Unreviewed; 212 AA.
AC A0A3P8NLL5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Homologous-pairing protein 2 homolog {ECO:0000256|ARBA:ARBA00016093};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000005687.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000005687.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000005687.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HOP2 family.
CC {ECO:0000256|ARBA:ARBA00007922}.
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DR AlphaFoldDB; A0A3P8NLL5; -.
DR STRING; 8154.ENSACLP00000005687; -.
DR Ensembl; ENSACLT00000005809.1; ENSACLP00000005687.1; ENSACLG00000003845.1.
DR GeneTree; ENSGT00390000006890; -.
DR OMA; QKYHREW; -.
DR OrthoDB; 25380at2759; -.
DR Proteomes; UP000265100; Chromosome 4.
DR Bgee; ENSACLG00000003845; Expressed in testis and 8 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR010776; Hop2_WH_dom.
DR InterPro; IPR040661; LZ3wCH.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR15938:SF0; HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG; 1.
DR PANTHER; PTHR15938; TBP-1 INTERACTING PROTEIN; 1.
DR Pfam; PF18517; LZ3wCH; 1.
DR Pfam; PF07106; TBPIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 8..68
FT /note="Homologous-pairing protein 2 winged helix"
FT /evidence="ECO:0000259|Pfam:PF07106"
FT DOMAIN 149..205
FT /note="Leucine zipper with capping helix"
FT /evidence="ECO:0000259|Pfam:PF18517"
FT COILED 81..145
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 212 AA; 24121 MW; FB6372230898E423 CRC64;
MSKKDNGAGV ILAYLNEKNR PYSAQDVFSN LQKQHGLGKT AVVKAMELLA LEGKIKEKIY
GKQKIYFADQ AQFKDVNDAD LKAIDHQISE LSEEVQSLTQ SCRQLDAELK ELNSSLTTEE
MVSEIQELKA ECSGYRARLE KIKSASNHIT PEEKDKVYKE RDLYVKEWKK RKRLASDMTN
AILEGYPKSK KEFLEEVGVE TDEDCKVVPP NT
//
