ID   A0A3P8NN46_ASTCA        Unreviewed;       341 AA.
AC   A0A3P8NN46;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Protein lifeguard 1-like {ECO:0000313|Ensembl:ENSACLP00000006220.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000006220.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000006220.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000006220.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000256|RuleBase:RU004379}.
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DR   AlphaFoldDB; A0A3P8NN46; -.
DR   Ensembl; ENSACLT00000006362.1; ENSACLP00000006220.1; ENSACLG00000004199.1.
DR   GeneTree; ENSGT01050000244890; -.
DR   OMA; EFIWASV; -.
DR   OrthoDB; 377780at2759; -.
DR   Proteomes; UP000265100; Chromosome 11.
DR   Bgee; ENSACLG00000004199; Expressed in spleen and 8 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd10428; LFG_like; 1.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR   PANTHER; PTHR23291:SF77; GLUTAMATE RECEPTOR, IONOTROPIC, N-METHYL D-ASPARTATE-ASSOCIATED PROTEIN 1B (GLUTAMATE BINDING); 1.
DR   Pfam; PF01027; Bax1-I; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004379};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU004379};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU004379}.
FT   TRANSMEM        134..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        167..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        223..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        254..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        279..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
FT   TRANSMEM        313..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004379"
SQ   SEQUENCE   341 AA;  37307 MW;  9DD309279C767707 CRC64;
     MTTEKTEYTP VVVGASQPPL PGQPAFPVAF GTNVPGPSTL EGHVPGAGVH PFPPPTAFAP
     GVPGDFGMAV NPNQGQSGFA NPSYPAYPPP AYGFNENIAG EVFHNEDPPA FHENQEFDFG
     LDNKTIRRAF IRKVFLVLTA QLMVTFAFVA VFTFVEQVKV FVAANMWTYL VSYIVFFVSI
     CVISCCGNVR RRHPWNLVAL SILTLSMSYM VGMIASFHET DSVIMAVGIT AIVCFTVVIF
     SLQTKYDFTS CYGVLFVCLI VLIVFGFLCI FIRDKILHIV YAGLGALLFT CFLAVDTQML
     LGNKELALSP EEYVFAALNL YTDIINIFLY ILAIIGRARG G
//