ID   A0A3P8NRM3_ASTCA        Unreviewed;      1397 AA.
AC   A0A3P8NRM3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Condensin-2 complex subunit D3 {ECO:0000256|PIRNR:PIRNR036508};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000007328.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000007328.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000007328.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Regulatory subunit of the condensin-2 complex, a complex
CC       which establishes mitotic chromosome architecture and is involved in
CC       physical rigidity of the chromatid axis.
CC       {ECO:0000256|PIRNR:PIRNR036508}.
CC   -!- SUBUNIT: Component of the condensin-2 complex.
CC       {ECO:0000256|PIRNR:PIRNR036508}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR036508}.
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DR   STRING; 8154.ENSACLP00000007328; -.
DR   Ensembl; ENSACLT00000007493.1; ENSACLP00000007328.1; ENSACLG00000004944.1.
DR   GeneTree; ENSGT00940000153566; -.
DR   OMA; RIHPNIC; -.
DR   OrthoDB; 38442at2759; -.
DR   Proteomes; UP000265100; Chromosome 13.
DR   Bgee; ENSACLG00000004944; Expressed in ovary and 4 other cell types or tissues.
DR   GO; GO:0000779; C:condensed chromosome, centromeric region; IEA:UniProtKB-UniRule.
DR   GO; GO:0000796; C:condensin complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR026971; CND1/NCAPD3.
DR   InterPro; IPR032682; Cnd1_C.
DR   InterPro; IPR012371; NCAPD3.
DR   PANTHER; PTHR14222; CONDENSIN; 1.
DR   PANTHER; PTHR14222:SF1; CONDENSIN-2 COMPLEX SUBUNIT D3; 1.
DR   Pfam; PF12717; Cnd1; 1.
DR   PIRSF; PIRSF036508; Condns_HCP-6; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Cell cycle {ECO:0000256|PIRNR:PIRNR036508};
KW   Cell division {ECO:0000256|PIRNR:PIRNR036508};
KW   DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW   ECO:0000256|PIRNR:PIRNR036508}; Mitosis {ECO:0000256|PIRNR:PIRNR036508};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036508}.
FT   DOMAIN          940..1106
FT                   /note="Condensin complex subunit 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12717"
FT   REGION          158..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1255..1274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1374..1397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..183
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1397 AA;  156809 MW;  E284B666810DA609 CRC64;
     MDLISALQFL RLNDVPEAWV DAVWEVEFTE RKPLDKTIEE ELTARREKSF TALYQCLLAH
     ADQYQSAGSD GASQSVWAVL VESGISVKSV VAVLSFFVLA GKSKVASGHQ RVNSLCAASV
     YLLLLRTPGS ISNKVFHEVL LDTCLDLTRH CWPQDSEKKR KKDLKSSQTE GKRSRPQRKD
     SPEMEMEEED EEEEEVHLSG KDLMRIRDAV ALLVQSLLRL LQTFPLKDSP QTMIHCMQIF
     SNLLYFEPTT GKPAFAAEQD VTKLRSIPEM AFYGLQLLCL PKHGDQKESL RRVFHQLLYV
     ILMMKKGNTG KPSLLVPSQT VLATRDQAIQ FVCHLVDELK QLALPFLQIL LQHICFQMVE
     KNEYRSHGAQ AVGMLTSQMA SEDYACFIKW LCNFSRSSKM VHRLFSVDVV MVLLEQPERR
     PEECRDPDLV CFLMHSSLIQ NLLFARRMDE SPTVQGHALN CLAQCLELPS LNATRAIHNL
     FSATGTQTVL EGEITEGTLS TQHTLKTYRT LPFRTVELSS TDSAACYAKE NLALLLRRVK
     DSKTNVRKAA LQALLGLLKH DVIPMSWETL QTLSERCRDP SVSVKKKALQ CVGDLLSVKP
     ECSVVQKAWL QGVVPAVADS ETSVQDKALE ALDQVLLSQV KPYSAGCHLD ASQRLMWELL
     GLLCHQCQKL SRYFSKAFTI WSKQKKFTPL FVSNLISHTE ADHAAGAWLL LSKVVSSSSR
     LPHGKILDAW DKMVRSKDVN ATTCCHILCV MGDIAVHLNE DTKERVVADL MSWLKTFTLP
     LEVISSAVQT LYQFGCSEDI KQTQAFLNQR CGELVSACES YLASIILTDN GAQNLDEELM
     VKHLHTLGVA SLQCPAKVNK RTVLLVESVL TTHSEKLAEC QTELPASLPL SQFKANWLPT
     RVRAHGVITL GKLALQSEEL AQKYLPVFAR ELEVGTEVSV RSNVVVIMCD LCVRYTNMVD
     HYIPNISACL RDKDAVIREQ TLIMLTNLLQ EEFVKWKGSL FFDFMVALVD PVPAIVSLTE
     YCLLHLLLKK NPEMFSQHFI ECIFHFNSYT KHKSYNKFSQ SERERVHFSL KGEQYREKRF
     RIYCFLLEHF TDAQRFNITN KINQTILACF ADEELPLDAD GANILSETFN ILSLKEFKLQ
     TICSSAGAAA GEEAEEENMA TMAKAVLQAA QKKVVSQVRK KAFIENTVPL IISLKNLLEQ
     KRSPVLRDLV GYLQVTMQDY RNEVKEILSG DEQLAAEMEF ALKIAEKERA TVEQLDNDSL
     AGDGKKAQGS AQRSPVRSTA LLPCTFATPQ PPRPNLQTAR LALTDRVRGP RRQDDVQSKS
     IALEGTVMAK GAASDRAIST PKGVKINLTF DEGLSAILSE QGTSEEGSVL HVRSSEAQAP
     GPRQWNVQSP LRLRKRL
//