ID A0A3P8NRY6_ASTCA Unreviewed; 425 AA.
AC A0A3P8NRY6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=ADP ribosylation factor GTPase activating protein 1 {ECO:0000313|Ensembl:ENSACLP00000007557.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000007557.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000007557.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000007557.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8NRY6; -.
DR STRING; 8154.ENSACLP00000007557; -.
DR Ensembl; ENSACLT00000007726.1; ENSACLP00000007557.1; ENSACLG00000005117.1.
DR GeneTree; ENSGT00890000139515; -.
DR OMA; MSKLWEV; -.
DR Proteomes; UP000265100; Chromosome 5.
DR Bgee; ENSACLG00000005117; Expressed in brain and 8 other cell types or tissues.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08830; ArfGap_ArfGap1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 7..124
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 127..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 46968 MW; 5040A4227D15D1CA CRC64;
MASPRTRRVL KEVRTQDENN LCFECGAFNP QWVSVTYGIW ICLECSGKHR GLGVHLSFVR
SVTMDKWKDI ELEKMKAGGN GKFRLFLELQ DDYDPNWTLQ EKYNSRAAAL FRDKVATLAE
GKEWSIETSP ARNWTSPQPK STLSSSHRSG GSGQNSAKSS DKAFEDWLSD DVNSYQSGGG
YSGNQENRYV GFGNTVTPEK KEEDFLNNAM SSIYSGWSSF TVGASKFASI AKDNTTKLAN
QATLKLRGYK APPEPATELG QTLNENVIKP TQEKVKDGKL LDEMAVSITG LANKVQGAGS
KLTNLFSGKQ EDGSAGESYQ NMDATEGYQG SSSQPVARDF WETFGSNSSL KAKKSPSSDS
WTIADNSAKK SSDSWDNWGS EAASNNKHST EESWEAWDNN WENADGKTKK SPTKPAEETW
ENADW
//
