ID   A0A3P8NVJ6_ASTCA        Unreviewed;       540 AA.
AC   A0A3P8NVJ6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Lactase {ECO:0000313|Ensembl:ENSACLP00000008739.1};
GN   Name=LCT {ECO:0000313|Ensembl:ENSACLP00000008739.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000008739.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000008739.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000008739.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC       {ECO:0000256|RuleBase:RU003690}.
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DR   AlphaFoldDB; A0A3P8NVJ6; -.
DR   Ensembl; ENSACLT00000008943.1; ENSACLP00000008739.1; ENSACLG00000005605.1.
DR   GeneTree; ENSGT00940000155324; -.
DR   Proteomes; UP000265100; Chromosome 16.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   540 AA;  60749 MW;  831D3A6A3A36F2A8 CRC64;
     MDFNWSYNYI LFLFESFPSG FQWATSSVSF KTEGGWSEGG KGETIWDRFG HEGLAFANQT
     ADLACDSYRK VDYDVYLLRG LQVDTYQFSI SWARIFPTGY RQSQSEKGAQ YYDQLINALV
     ASGIQPIVTL YHWDLPQALQ NYGGWTNASI VEAFKDYADF CFSRFGDRVK IWNTFNSPWV
     VSHAGYGTGV HAPGVKDYVE SSYQVTHNIL KSHAEAWHVY NDNYRKTQGG KVGIALNSDW
     AEPSDPAKPE DVAAADRYLQ FMLGWFAHPI FVDGDYPAIL KDQVEQKKTA CPDSVPAKLP
     VFTPTESKRI LGTADFFGLN HYTSRLVSNS DGGCTPGPDG VGDFHATVDP TWSSTASDWI
     YPVPWGLRRL LNYIATEYLS ANKLPVYITG NGMPTDYSVD SLTDTSRMDY MRSYINEALK
     ATLTDGVDVQ RFTVQSLMDG FEANQGYSQR FGLHYVNFEV GSRPRTPKQS AYLYAEIIEQ
     NGFSSQKSKK FKAAERPLTR RLAALPPSEV PSQAKVVWEK FSSHLLKLVS LVLLQFLQVA
//