ID A0A3P8NW90_ASTCA Unreviewed; 616 AA.
AC A0A3P8NW90;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=E3 ubiquitin-protein ligase MSL2-like {ECO:0000313|Ensembl:ENSACLP00000009017.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000009017.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000009017.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000009017.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8NW90; -.
DR STRING; 8154.ENSACLP00000009017; -.
DR Ensembl; ENSACLT00000009222.1; ENSACLP00000009017.1; ENSACLG00000006145.1.
DR GeneTree; ENSGT00390000016814; -.
DR OMA; GPQECNG; -.
DR OrthoDB; 4153116at2759; -.
DR Proteomes; UP000265100; Chromosome 19.
DR Bgee; ENSACLG00000006145; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0072487; C:MSL complex; IEA:InterPro.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR CDD; cd13122; MSL2_CXC; 1.
DR CDD; cd16522; RING-HC_MSL2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR037922; MSL2.
DR InterPro; IPR032049; Msl2-CXC.
DR InterPro; IPR032043; Msl2_Znf-RING.
DR InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16048:SF3; E3 UBIQUITIN-PROTEIN LIGASE MSL2; 1.
DR PANTHER; PTHR16048; MSL2-RELATED; 1.
DR Pfam; PF16682; MSL2-CXC; 1.
DR Pfam; PF16685; zf-RING_10; 1.
DR SMART; SM01114; CXC; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 4: Predicted;
FT DOMAIN 485..532
FT /note="Tesmin/TSO1-like CXC"
FT /evidence="ECO:0000259|SMART:SM01114"
FT REGION 145..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..465
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 66546 MW; A51172E6874813B2 CRC64;
MNPVNATALY VSASRAVLQC DPRQPHSFAE MYKLLPFFRK SLACLVCGKL LQDPISQTHP
ECQHYVCLGC KGQKMQIRPS CSRCKDHSSF QENKQLSLLV QCYRKLCFYV IHSPLLLCVS
NHVGGSPEVM ALLEEVLLSH KDEMEDPSLV HEDVNPSAPE SLTPTEAPPA PAELSAVPQS
SSSDPPCFNG PQECNGDVLE DVDPSSPELE VCELVEEQAQ AGLSVSNTGC GGLELSLTTG
RLAPTPGTVC SLRDGDSSSR EVEEGEVLLL SVEEVLQTLD PLQPGRDSLH TQPVRTHTHT
HTAMDRAHTQ MYIQLDAAHN YTQIQTGRTN TVAGHGAHTH TSSFDPPSAS KPPPVRLNRK
RSHSESDREK VKPLPIASIL QGSSSNSHTP NPSHTLHTHP PTPSLTVPAH TYSSLPNGAP
PKPSRPAPNH NKGARKHPEP SPKKPHVKAR TGGASKTKER SKDQRLMAGC LVPPAPARPP
YKKPVEKKGC KCGRATQNPS VLTCRGQRCP CYSNRKACLD CICRGCQNSY MANGEKKLEA
FAVPEKALEQ TRLTLGINLT SITAAAALRN PATTSIRANT LLNVATATGT PVSTAFLSPS
PPQEPNYEES LELLIG
//
