ID   A0A3P8NWB8_ASTCA        Unreviewed;       657 AA.
AC   A0A3P8NWB8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000009088.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000009088.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000009088.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8NWB8; -.
DR   STRING; 8154.ENSACLP00000009088; -.
DR   Ensembl; ENSACLT00000009301.1; ENSACLP00000009088.1; ENSACLG00000006203.1.
DR   GeneTree; ENSGT01060000248639; -.
DR   Proteomes; UP000265100; Chromosome 18.
DR   Bgee; ENSACLG00000006203; Expressed in liver and 4 other cell types or tissues.
DR   GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   InterPro; IPR015095; AlkB_hom8_N.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR47510; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47510:SF3; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF09004; ALKBH8_N; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
FT   DOMAIN          238..506
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   657 AA;  74601 MW;  1CB91F509BF21A28 CRC64;
     MSELLVMLRS VLTAGLHPDM LSGTDTPEEA REVASSSYCI RSNKTEIIQF NTLCSKKKII
     RMSWAFFTFI GQCRTEECRT EEGLMTGEMD PYKAASYNVR RAVKEAKQRY GRKLESQLQQ
     SDSRSLWRGL RTITDYKAPT TGMTNAAVTL ADELNTFYAR FEAAAKDSNN ASVSGANGCR
     QEDTASTGNV LVISEHEVRR AFKRVNTRKA AGPDGIPGRI LRDCAYQLAP VFTEIFNISL
     SQSVIPTCFK ESIIVPVPKK PHPASLNDYR PVALTSVVMK CFERLVRDFI ISSLPDTLDP
     LQFAYRPNRS TDDAISHLLH TSLTHLDTRR GNYVKMLFID YSSAFNTIIP STLTTKLEHL
     GLSSSMCLWI SNFLTGRPQA VRMGGHVSAS TTLSTGAPQG CVLSPLLYSL YTYDCVATTS
     STTIIKFADD TVVVGLISDN NETAYLKEIR NLENWCQRNN LLLNISKTKE LIVDFSTKQE
     RNYQTPVINE CPVERVDSFK YLGVHITQDL SWSCHINTVV KKARQRLYHL RRLRDFQLPS
     KVLRNFYSCT IESILTGNIL TWFGNSTMQD RRALQRVVRS AERTIRSELP DLHSIYSRRC
     WTKARKIVKD LSHPNNRLFS LLRSGKRFRS LKTNTERLRR SFFPQAIRSL NHTTTQY
//