ID   A0A3P8NXU5_ASTCA        Unreviewed;       953 AA.
AC   A0A3P8NXU5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000009626.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000009626.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000009626.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8NXU5; -.
DR   Ensembl; ENSACLT00000009849.1; ENSACLP00000009626.1; ENSACLG00000006558.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   Proteomes; UP000265100; Chromosome 9.
DR   Bgee; ENSACLG00000006558; Expressed in anal fin and 5 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 6.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          78..212
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          761..953
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   953 AA;  106854 MW;  C7368D458EE92663 CRC64;
     LKKKFQCVFE GIAKAGNPTL LNQIYTELYI TEGGTAEVNE EHEVRQIETA SRKPHRPETT
     IRQEDIFKAS PGRDEPIRTV LTKGVAGIGK TVLTQKHSLD WAEDKANQDI QFIFPITFRE
     LNVLKEEKFS LVGLVHHFFT ETKEAGICSF EDFQVVFIFD GLDECRLPLD FHKTTILTDP
     RKSTSVDVLL INLIRGKLLP SARLWITTRP AAANQIPPDC VGMVTEVRGF TDPQKEEYFK
     KKVSDEKQAS SIISHIKTSR SLHIMCHIPV FCWITATVLE DVLETREGGQ LPKTLTEMYI
     HFLVVQAKVK KIKYDGGAET DPHWSPESRT MMESLGKLAF DQLQKGNLIF YESDLTECGI
     DIRAASVYSG VFTQIFKEER GLYQDKVFCF IHLSVQEFLA ALHVHLTFIN SGLNLMQEQQ
     TTSRWFKPSL HQSAVNKALQ SPNGHLDLFL RFLLGLSLQT NQTLLRGLLT QTGSSSQTNQ
     ETVQYIKKKL SENLSAEKSI NLFHCLNELD DRSLVEEIQQ SLRSGSLSTG KLSPAQWSAL
     VFILMSSEKD LDVFDLKKYS ASEEALLRLL LSVPNLSERG YEALSSVLSS QSATLRELDL
     SNNNLQDPAV RYLSAGLRSP HCKLNTLRLS HCKLSERGYE ALSSALSSQS SSLRQLDLSN
     SDLQDSGVKL LSAGVKSPHC KMETAFIDSF GFLYSFLHHL NSSDVLCFCS LSGCLITEEG
     CTSLASALSS NPSHLRELDL SYNHPGDSGM KLLSAGLKDP DDGSITAAGL CLFSPSDSCQ
     LTIDTNTVNT NLQLSDNNRK VTRVRKVQSY PDHPDRFDVW EQLLCRNGLT GRCYWEVEWR
     GNVYISVSYR SIRRKGYGDD CVFGCNDQSW SLYCDYNGPR YVWHNNRQTS ISSSSSVSNR
     AAVYVDCPAG TLSFYRVSSD TLIHLHTFNT TFTQTLYPGF VLDWPPGSSV SLC
//