ID   A0A3P8P065_ASTCA        Unreviewed;       475 AA.
AC   A0A3P8P065;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Islet cell autoantigen 1-like {ECO:0000313|Ensembl:ENSACLP00000010417.1};
GN   Name=ICA1 {ECO:0000313|Ensembl:ENSACLP00000010417.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000010417.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000010417.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000010417.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8P065; -.
DR   STRING; 8154.ENSACLP00000010417; -.
DR   Ensembl; ENSACLT00000010668.1; ENSACLP00000010417.1; ENSACLG00000007114.1.
DR   GeneTree; ENSGT00390000005530; -.
DR   Proteomes; UP000265100; Chromosome 11.
DR   Bgee; ENSACLG00000007114; Expressed in brain and 2 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR   CDD; cd07661; BAR_ICA69; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR010504; AH_dom.
DR   InterPro; IPR024114; Islet_autoAg_Ica1/Ica1-like.
DR   InterPro; IPR006723; Islet_autoAg_Ica1_C.
DR   PANTHER; PTHR10164; ISLET CELL AUTOANTIGEN 1; 1.
DR   PANTHER; PTHR10164:SF3; ISLET CELL AUTOANTIGEN 1; 1.
DR   Pfam; PF06456; Arfaptin; 1.
DR   Pfam; PF04629; ICA69; 2.
DR   SMART; SM01015; Arfaptin; 1.
DR   SMART; SM01237; ICA69; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS50870; AH; 1.
PE   4: Predicted;
FT   DOMAIN          53..256
FT                   /note="AH"
FT                   /evidence="ECO:0000259|PROSITE:PS50870"
FT   REGION          282..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   475 AA;  54230 MW;  11CDCFB1E3AD5ED0 CRC64;
     MEGGNFGYSR DYLDRFIQSQ DSSVVNKFQQ KYWKTKQTLI KVTGKKEDEH VVASDADLDA
     KLEVFHSIQR TCMELLKVIE QYQRRICILS QEENELGRFL RSQGSQDKTR AGKIMQATGK
     ALCFSSQQRL ALRNPLCRLY QEVETFRYRA ISDTWLTVNR MEQSRTEYRG ALLWMKDVSQ
     ELDPDTHKQM EKFRKVQAQV RTTKTSFDKL KNDVCQKVDL LGASRCNLLS HVLTTYQTTL
     LHFWEKTSHT MAAIHESFKG CQHYEFSTIK TLQDPVDKLA KKKGKNKVKA ETEEAKKEET
     TDDQLISLVN ENTSDKAREE SEGEETDSMA LLNEILGGLS VDEGDFSQEW TEVFGETEEG
     TSAASTRPTE AQDKENFFLP SQLLDQSLNN LQSSISGQPV CVCVCVCVCV CVCVCVCVCV
     CVLQLCYYTR VNQKIGKLVQ GSSLVIKRID HLDFAPLDRF SHHDHHAEPG KISHH
//