ID A0A3P8P269_ASTCA Unreviewed; 557 AA.
AC A0A3P8P269;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Coenzyme A synthase {ECO:0000313|Ensembl:ENSACLP00000011105.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000011105.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000011105.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000011105.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8P269; -.
DR STRING; 8154.ENSACLP00000011105; -.
DR Ensembl; ENSACLT00000011384.1; ENSACLP00000011105.1; ENSACLG00000007630.1.
DR GeneTree; ENSGT00550000075078; -.
DR OMA; TQCLQSY; -.
DR OrthoDB; 460288at2759; -.
DR Proteomes; UP000265100; Chromosome 8.
DR Bgee; ENSACLG00000007630; Expressed in testis and 8 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:InterPro.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.
DR CDD; cd02022; DPCK; 1.
DR CDD; cd02164; PPAT_CoAS; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00376; Dephospho_CoA_kinase; 1.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR001977; Depp_CoAkinase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00152; dephospho-CoA kinase; 1.
DR PANTHER; PTHR10695:SF64; BIFUNCTIONAL COENZYME A SYNTHASE; 1.
DR PANTHER; PTHR10695; DEPHOSPHO-COA KINASE-RELATED; 1.
DR Pfam; PF01121; CoaE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51219; DPCK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..557
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018302556"
FT DOMAIN 189..333
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
SQ SEQUENCE 557 AA; 61710 MW; 46C715BB51967412 CRC64;
MSMFSTGILV LTSPLHTLPL RIAPVLSSAA QRVERTLYVH LHPGLNLGSG SQPRPVFIPP
AVDLSNLITR LYSNAADVCG HLDVCVLLTN VRTQSVACSG ATTPNGPFPT PQALSNSPEV
VLTDFAPQDP GQTHQVTQCL QSYTGHCYAC RPGLPSVLLH SELMKLQEED VPEAQQEKAE
PLQTYNDVVV GGTFDRLHGA HKTLLSISCL LANRRFLIGL CDHAMLKKKV LKELIEPYSV
RVQRLQEFLQ DVKPSLQVEV VPLDDPFGVS VVDPLLECIV VSEETRKGGE AVNKKRTENG
LPALVLHEIQ LLKDAHHTEI EEEKISSSSL RARLLGTLLT PPKDNSHLPP LPYVIGLTGG
SGSGKSAIAK QLEAFGAVWI DCDKLGHEVY QPDAAAYHRV LEEFGSDILS EDKTINRRAL
GRKVFGNQVR LKALTDIVWP EIALLVQKRI NQARDEDKQV CVVDAAVLLE AKWQNLVHEV
WVTIIPEEEA VLRITERDGV TTEDALRRLQ SQWSNSKQVE HANVVLSTLW EPEVTRKQVL
KAWNLLQKRI QQKHEGH
//
