ID A0A3P8P3V9_ASTCA Unreviewed; 897 AA.
AC A0A3P8P3V9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Potassium voltage-gated channel subfamily KQT member 5-like {ECO:0000313|Ensembl:ENSACLP00000011700.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000011700.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000011700.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000011700.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3P8P3V9; -.
DR Ensembl; ENSACLT00000011988.1; ENSACLP00000011700.1; ENSACLG00000007969.1.
DR GeneTree; ENSGT00940000155933; -.
DR Proteomes; UP000265100; Chromosome 6.
DR Bgee; ENSACLG00000007969; Expressed in ovary and 4 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 6.10.140.1910; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR PANTHER; PTHR47735:SF8; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01459; KCNQCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..337
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 396..505
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 840..897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..855
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..889
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 897 AA; 97441 MW; C06F58A9FA5CF9F1 CRC64;
MPRNHSGDEG GTGLWMRTSP GHRTEGYGLK DVESGGKMMN NAGDGLLSAP GAAGAAGSDN
ARGKQGARLS LLGKPLLYST QSGRRNVRYR RLQNYLYNVL ERPRAWAFIY HAFVFVLVFS
CLVLSVFSTI PAHQEFSSYC LLILEFVMIV VFGLEFIIRI WSAGCCCRYR GWQGRLRFAR
KPFCVIDIIV LIASVAVVSA GSQGNIFATS VLRSLRFLQI LRMVRMDRRG GTWKLLGSVV
YAHSKELVTA WYIGFLVLIF SSFLVYLVEN KFNNEFATYA DALWWGTITL TTIGYGDKTP
KTWTGRMLSA GFALLGISFF ALPAGILGSG FALKVQEQHR QKHFEKRRNP AAYLIQCVWR
SYAADENSVS IATWKPHLKA LHTCSPTKKE QGESTTRIMK FHVAKKKFKE TLRPYDVKDV
IEQYSAGHLD MLCRIKSLQT RVDQILGKGQ IPLDKKIRDK LLSDGDILED MSMLGRVCKV
ERQVQSIESK LDSLLDIYRQ VLRKGSSSAL TLSSLPLFEL EQTSDYHSSV FSKDMSCSTQ
VSSSGAPPTS GFVTRSSTSS HLSQGGLHLI LGPPNELNLN LNAPSSTPPS GLASSSFSPS
PLPHHHHHRH HHHPQAQATT PESGTDEAMG SSPPILTPNS VSSSGDRGVR DGGFPLLARL
PPPPPPSRSH GPGTLVRTAS IEVSPDIEDF CGGLGTQMED SVVGKGLGLG LNRLGQQLQG
NSNSRLSTKE EGSWRRQMSL ELEPLVPPAL GCCSGSNEMD RGLGKSMSVQ DLKQVAPTHH
GHSLSSPSPS TSSDSPIGFH SCSQDPGGGG GGTGRRSGGG WGEEDLFISD RDIETQGLDF
LSQGSAETPT YSSELLRTGG RAGAGTQGSN RSLASGHASL PSTGSNELLN MPHVRLK
//
