ID A0A3P8P527_ASTCA Unreviewed; 301 AA.
AC A0A3P8P527;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Transcription factor Spi-B-like {ECO:0000313|Ensembl:ENSACLP00000012101.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000012101.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000012101.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000012101.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR AlphaFoldDB; A0A3P8P527; -.
DR STRING; 8154.ENSACLP00000012101; -.
DR Ensembl; ENSACLT00000012400.1; ENSACLP00000012101.1; ENSACLG00000008262.1.
DR GeneTree; ENSGT00940000155067; -.
DR OMA; ANMGHQT; -.
DR OrthoDB; 3980839at2759; -.
DR Proteomes; UP000265100; Chromosome 20.
DR Bgee; ENSACLG00000008262; Expressed in anal fin and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF312; TRANSCRIPTION FACTOR PU.1-LIKE; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 204..287
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 161..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..197
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 301 AA; 34333 MW; 75CBECF65F928EF5 CRC64;
MGFMRRKKEN KTKWVLCVIV TPQAITDNRY NKCKCSLCPA VCVCQMAYAT ELKLSGGRGA
WSGVAPSSCP EVDLEVIEEY LQEHSLEVQP AHMPASPLTS MGQHIHSHQG SRIIENSWSG
QHAYEWHCGS HSEEYRQQPQ AWPSPHDNQW GHIAYSDEAS GYIDSDSQSS SSQYQDSPSP
SSDTGSRKDR DPLPLAPLSG KRKERLFQFL FEMLQTPSMR SCIWWVQSSS GTFQFSSQNK
ESLAQLWGRR KGNRKPMTYQ KMARALRNYS RTGEIHKVKR KLTYRFDEKT LKCLQGDSNT
K
//
