ID A0A3P8P579_ASTCA Unreviewed; 1167 AA.
AC A0A3P8P579;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Protogenin B-like {ECO:0000313|Ensembl:ENSACLP00000012156.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000012156.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000012156.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000012156.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8P579; -.
DR STRING; 8154.ENSACLP00000012156; -.
DR Ensembl; ENSACLT00000012455.1; ENSACLP00000012156.1; ENSACLG00000008277.1.
DR GeneTree; ENSGT00940000155943; -.
DR OMA; EGTHTMA; -.
DR OrthoDB; 5397809at2759; -.
DR Proteomes; UP000265100; Chromosome 7.
DR Bgee; ENSACLG00000008277; Expressed in ovary and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 5.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 5.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1167
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017969564"
FT TRANSMEM 938..960
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..120
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..212
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 225..312
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 317..396
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 411..505
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 507..603
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 608..703
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 713..806
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 811..906
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1081..1128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1081..1120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1167 AA; 128477 MW; A0BEED18C8D72B76 CRC64;
MAHFKMKFFR HWLLFVLCLP LSSVLCFSEL SFITEPSDVT VLPKDPAVLD CQAHGQPPVT
IKWLRNGVKL AESEHIHFLP NGSLYIPKIK HTKEDSDEGF YQCLSQNKFG AILSQRSRLT
IASISEFVLH PVPVVVTVGS VARFSCAVIS SPPATITWEL NQRTLPLQTD RITVLPNGVL
QIHNVQLEDA GHYQCVATNI GSVLKSREAT LTVNLDAGPK LRQRPRIIAG PQNVTVSLHQ
TVVLECVATG NPRPIISWSR ADSKSIDVYN AKVLGNGNLV ITDVSTKHSG VYVCRATTPG
TRNHTTAAAN LTVLVPPNIV EKPESQTRPR AGTARFMCQA EGVPTPRITW LKNGEQVHLN
GRIKMYNSKL VITQIIPEDD AIYQCVAENE QGSVLSLARL IVVMSEDRPS APRNIHAETI
SSSAILLAWE RPLYNTDKVI AYSVHYMKAE GLNNEEYQVV IGNDTTSYII DDLEPARNYS
FYIVAYMPMG ASRMSDQVSQ HTLEDVPLRT PELSLTSQST TDIQVSWQPL PAKVSRGRVS
AYRLSYRTAA DSTVTSVELL QNSTEYLLEG LQPDTIYLLR MAAATRVGWC EPSAWTSHRT
PKTSSNKVPS APILQLEALN CTSIVARWQS SLESVAIQGY RLCYHEEGQP EQPDIQLQAQ
TNTYTIGGLD PRKKYHVKIL AVSKVADGHQ RDQTISTPGC VSARDQLAAA PPPPNQVTVL
DGNSSAVSLR WSHPPFPSGK AVSYTVRCTP VGTHNVFAIR YLQTTKQSVT VQKLDPNTRY
EFVVRLHVDQ MSSPWSSVVY HQTLPAAPSQ PPAGVRVTLI EEDTALVSWR EPTESNVVIT
RYTILYASQK DWIAGHWQKV QREGSHTMAL LEKLEPGNVY LVKIAASSEV GEGPFSEIVE
LAPKRGNVHR SKNPRHSDWF PDSTVFSDGL YHIDQRSMTG IIVGVSIALT CIITCALILI
SKGKQRKSSS HKVIAVGAPE GPRSGFPSER HSENIEALIP MMSDHFIDAK GGSSIIINGT
GPVSSKKWLL FNREIRNPAD SDIETRASLY EAGKTVLRYE EHLGSAPLPP SSREIIYGPL
RSESSHTSEG SQETGDSGHY SNEESNEEMS SPSSSRSSRP ESLGPDDRIA VLELKQSFKV
EKEVDASLLR GISEAHVVSS TCQAASC
//
