ID   A0A3P8P8E6_ASTCA        Unreviewed;       340 AA.
AC   A0A3P8P8E6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Transposase Tc1-like domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000013255.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000013255.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000013255.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8P8E6; -.
DR   STRING; 8154.ENSACLP00000013255; -.
DR   Ensembl; ENSACLT00000013585.1; ENSACLP00000013255.1; ENSACLG00000009079.1.
DR   GeneTree; ENSGT01030000234537; -.
DR   Proteomes; UP000265100; Chromosome 16.
DR   Bgee; ENSACLG00000009079; Expressed in muscle tissue.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR038717; Tc1-like_DDE_dom.
DR   InterPro; IPR047655; Transpos_IS630-like.
DR   InterPro; IPR002492; Transposase_Tc1-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; NF033545; transpos_IS630; 1.
DR   PANTHER; PTHR23022:SF138; TRANSPOSABLE ELEMENT TC3 TRANSPOSASE; 1.
DR   PANTHER; PTHR23022; TRANSPOSABLE ELEMENT-RELATED; 1.
DR   Pfam; PF13358; DDE_3; 1.
DR   Pfam; PF01498; HTH_Tnp_Tc3_2; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
PE   4: Predicted;
KW   Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT   DOMAIN          71..140
FT                   /note="Transposase Tc1-like"
FT                   /evidence="ECO:0000259|Pfam:PF01498"
FT   DOMAIN          149..300
FT                   /note="Tc1-like transposase DDE"
FT                   /evidence="ECO:0000259|Pfam:PF13358"
SQ   SEQUENCE   340 AA;  39049 MW;  8BC494465D83E8B9 CRC64;
     MAKTKELSKD TRKSIVDLHQ TGKSESTIGK QLGVKKSTVG AIIRKWKTYK TTDNLPRSGA
     PRKISSRGVK MIMRTVSKDP RTTRGDLVND LQRAGTKVTK VTISNTLQRQ GIKSRSARRV
     PLLKPVHVQA RLKFAREHMD DTAEDWENVM WSDETKVEHF GINSTRRVWR KKNTELHPKN
     TVPTVKHGGG NIMLWGCFSA KGTGRLIRVK DRMNGAMYRE ILSQNLLPSV RTLKMKRGWV
     FQHDNDPKHT ARATKEWLRK KHLKVLEWPS QSPDLNPIEN LWRELKVRVA RRQPQNITAL
     EKICMEEWAK IPATVCANLV KTYSKRLTSV IANKGYVTKY
//