ID A0A3P8PES3_ASTCA Unreviewed; 426 AA.
AC A0A3P8PES3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000015512.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000015512.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000015512.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8PES3; -.
DR STRING; 8154.ENSACLP00000015512; -.
DR Ensembl; ENSACLT00000015873.1; ENSACLP00000015512.1; ENSACLG00000010566.1.
DR GeneTree; ENSGT00940000163564; -.
DR OMA; MSEDIPF; -.
DR Proteomes; UP000265100; Chromosome 2.
DR Bgee; ENSACLG00000010566; Expressed in brain.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 3.
DR Gene3D; 2.60.40.60; Cadherins; 3.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF332; PROTOCADHERIN1-ALPHA-AV3-RELATED; 1.
DR Pfam; PF00028; Cadherin; 2.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 3.
DR SUPFAM; SSF49313; Cadherin-like; 3.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 3.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..426
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018175179"
FT DOMAIN 65..122
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 123..230
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 239..336
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 426 AA; 46382 MW; 6F0AE20B1656D614 CRC64;
MGRSVDLGTQ CWWVAISFSL MLSCVERVSA QIKYSVPEEV KVGSVVGNVA KDLGLDISSL
EKRRFRIVSG VPFLVLQKSL DREKESEHKL ILTAIDGGNP PRSGTVNVTV IVLDSNDNHP
TFSQEVYYAT VRENTDAGVF VIKLNATDLD EGLNGQIEYF FGEELKGNLY EIFNMDKDTG
ELRINGEIDF EKTDIFKLDV HATDKGQPPM SADCTVIISV LDVNDNKPEI EVTSLSKIVS
EDSKPGTVVA LISITDQDAG LNGKVICSLS DNIPFDLKPS FQDNMYSLVI KHKLDRESVS
HYDVTITATD CGVPPLSTSR TLSIDVSDVN DNAPQFAQNP VELYLVAGSS PGLDSLGRCV
FGQDTLLVAY WWWSEGPVAP VSGSLASVSA PQGGCGYNVA CHHQCVNVCV NGWMTGCVKR
FGALRD
//
