ID A0A3P8PJY4_ASTCA Unreviewed; 557 AA.
AC A0A3P8PJY4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM21-like {ECO:0000313|Ensembl:ENSACLP00000017288.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000017288.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000017288.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8PJY4; -.
DR STRING; 8154.ENSACLP00000017288; -.
DR Ensembl; ENSACLT00000017706.1; ENSACLP00000017288.1; ENSACLG00000011796.1.
DR GeneTree; ENSGT01040000240400; -.
DR OMA; PCITENW; -.
DR OrthoDB; 4166452at2759; -.
DR Proteomes; UP000265100; Unplaced.
DR Bgee; ENSACLG00000011796; Expressed in spleen and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd19802; Bbox1_TRIM8-like; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF32; BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 22-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51698; U_BOX; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 8..84
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT DOMAIN 15..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 149..189
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 350..545
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 190..296
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 557 AA; 63087 MW; 4824DC71FCA73D90 CRC64;
MSAASNLRSE DQFLCSICLD VFTDPVTTPC GHNFCKTCIS QHWDMSQSCQ CPMCKETFYT
RPQLKINTFI SEMVAQFRRE AQQKASSSSS EQQAAKPGEV PCDVCTGTRL KALKSCLLCQ
TSYCQTHLEP HLTVKGLKRH QLVDAVENLE GRMCTKHDNL LQLFCKTDQT CVCMLCPVLD
HKNHEFVPLR EEYEGKKAEL EKTEAEIQQM IQKRRLKIQE ITESVKMSKD AADRQKAEGV
QVLMALMESV ERRLKELMKE IEDKQEATEK QAEGLIKDLE QEISELMERS SEVEQLSRSE
DHLHLLQSFS SLKAAPPSKD WTEVRVHPPS YEGTVGRAVA QLEETVWKPM KKKLLEAAEL
QRVQQHEVDV TLDPDTANPY LILSDDGKQV YDSDVWKNLP DNPERFSLYV MVLGEQSFSS
GRFYFEVQVK GKTAWVLGVA TESINRKGDT TVSPQDGLWT VMLRNGNEYK ANAKYLVPLC
LHPGPEKVGV FVDYEEGLVS FYDVGAAALI YSFTGCSFTH KLHPYFSPSL NYGGKNSAPL
IICPVNQTDQ RLILLDE
//
