ID   A0A3P8PKG4_ASTCA        Unreviewed;       636 AA.
AC   A0A3P8PKG4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Ankyrin repeat and sterile alpha motif domain containing 3 {ECO:0000313|Ensembl:ENSACLP00000017546.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000017546.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000017546.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000017546.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8PKG4; -.
DR   STRING; 8154.ENSACLP00000017546; -.
DR   Ensembl; ENSACLT00000017966.1; ENSACLP00000017546.1; ENSACLG00000011990.1.
DR   GeneTree; ENSGT00940000156610; -.
DR   OMA; VIGLNWE; -.
DR   OrthoDB; 3674887at2759; -.
DR   Proteomes; UP000265100; Chromosome 8.
DR   Bgee; ENSACLG00000011990; Expressed in spleen and 5 other cell types or tissues.
DR   CDD; cd09519; SAM_ANKS3; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR047238; ANKS3_SAM.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR24184:SF6; ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF13637; Ank_4; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 6.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 4.
DR   PROSITE; PS50088; ANK_REPEAT; 4.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          67..99
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          100..132
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          133..165
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          167..199
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          407..470
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          228..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          309..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..249
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  69617 MW;  D18422645A03D5A6 CRC64;
     MSELSDDASE SEQLGASLSL WLGDSLLRAE ELDVPLDLHT ACSIGQYDVV AECIKKREVD
     LDGKNIGGWT PLMYASYIGH DNIANLLLEA RVNVNSTTAK GLTPLMLAAS CGNESIAYFL
     LQQGADLELK DSVGWTALFH CTSTGHQQMV KFLLDNNADA NVKEPGSGFT PLMEAAASGH
     EIIVQYLLDH KVKVDERNAK GETARALAMM YGYTKIVSLI DSRSPRMKPG HFEDLSSSED
     SDSAPPRIRS SRNRAKGISI HDGPQAIAKF RVGGTSKLCD PPAALPGDMM FRGIGEQSEG
     LCYRDVTSPI NELDGQSNSS RDDSPFFDHD MPTMRSSSSS EGLPHVIGLN WEGSVESNED
     SDQCKKSSIR RVNKGHHSKG KTRHGNSDGA HSSRTSNCGA GLPPSYTGPK DLAEFLEQIG
     FSKYLPLLEE QDIDLRIFLT LTENDLKEIG ITLFGPKRKM TSAIARWHSN ARPPSDALEQ
     AYADQLEAEM QEMAIQLHKR CEEVESLQSQ VSQEKELRTV MEGCLMEDKM AWKKVHAELV
     ENHRLAQNMS AMLGKERACR GELISCLTTD GISSSATAGE GTGVKAGEGA TCSSIQELMK
     KMDLYEEELA GSLQTLLQNL RRLSAPEKVS DSWERP
//