ID A0A3P8PKR2_ASTCA Unreviewed; 144 AA.
AC A0A3P8PKR2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Norrin cystine knot growth factor NDP {ECO:0000313|Ensembl:ENSACLP00000017534.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000017534.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000017534.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000017534.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}.
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DR STRING; 8154.ENSACLP00000017556; -.
DR Ensembl; ENSACLT00000017952.1; ENSACLP00000017534.1; ENSACLG00000011989.1.
DR Ensembl; ENSACLT00000017974.1; ENSACLP00000017556.1; ENSACLG00000011989.1.
DR GeneTree; ENSGT00940000166292; -.
DR OMA; CEGRCTQ; -.
DR OrthoDB; 2963739at2759; -.
DR Proteomes; UP000265100; Chromosome 16.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR004133; DAN.
DR InterPro; IPR003064; Norrie_dis.
DR PANTHER; PTHR28611; NORRIN; 1.
DR PANTHER; PTHR28611:SF1; NORRIN; 1.
DR Pfam; PF03045; DAN; 1.
DR PRINTS; PR01304; NORRIEDSEASE.
DR SMART; SM00041; CT; 1.
DR PROSITE; PS01185; CTCK_1; 1.
DR PROSITE; PS01225; CTCK_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..144
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040591862"
FT DOMAIN 51..144
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
SQ SEQUENCE 144 AA; 15652 MW; 0A0E56F016A083F1 CRC64;
MKPSISGGSP SGLLLVLMCC PLLGLVHSAS SSNKASDNGH AHLGDADPDR CMRHHFVETI
THPIYKCNSK MVLLARCEGH CSHTTRSDPL ISFSSVLKQP FKSTCSCCRP HTSKLKAVRL
RCTGGTRITA TYRYILACNC EECS
//
