ID A0A3P8PKX0_ASTCA Unreviewed; 851 AA.
AC A0A3P8PKX0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000017599.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000017599.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000017599.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8PKX0; -.
DR STRING; 8154.ENSACLP00000017599; -.
DR Ensembl; ENSACLT00000018018.1; ENSACLP00000017599.1; ENSACLG00000011969.1.
DR GeneTree; ENSGT00940000166432; -.
DR OMA; FFFVAVH; -.
DR Proteomes; UP000265100; Chromosome 2.
DR Bgee; ENSACLG00000011969; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF114; PCDH2G3 PROTEIN-RELATED; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..851
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018229342"
FT TRANSMEM 686..708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..133
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 134..240
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 241..345
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 354..450
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 451..560
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 582..671
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 851 AA; 92775 MW; A8D576C1B057C619 CRC64;
MGSAVYGRLA MNCYCVVFLF VDLHFAHGDV SYTIAEEMKV GFVIGNIAKD LGLGIATLSS
RKVRIDTDRD DKRYCDINLS TGDLTVSDRI DRESLCGKKA SCVLKEELVL ENPLELHRIS
IHVQDINDNA PEFSEDLISL EITESADKGA RFLLTEARDA DIGTNAVQRY NLQNNEHFTI
NTTSSGSKYG ELVLDTELDR EEQQEMKLLL TAMDGGSPQR SGTVVIHVIV LDANDNAPVF
TEAVYRASIP ENSPLKTPVI RVNASDADEG VNGEVTYEFS RLSDKLQKLF SLDPKTGEIL
VTGEIDYEEG SKYEVIVEVK DGYGLSSEAK VVIDITDVND NAPFINLKSL SNPIPENAPP
GTEVGIINVQ DRDSENNRQV RCSIQQGVPF KLVPSIKNYY SLVTTGQLDR ELVSDYNITI
TATDEGSPPL SSSKSVQLSV ADINDNPPVF EEQSYSAYVS ENNKPGSTLC SVSARDPDWR
QNGTVVYSLL AGEVNGAPVS SYLSVNGDTG VIHAVRSFDY EQFRSFKVHV MARDNGSPPL
SSNVTVSVFI SDVNDNSPQI LYPSPGGNSF MTELVPKVAH GGSLVSKVIA VDADSGQNAW
LSYQIVKSTD PGLFTIGVHS GEIRTQRDIS ESDSMKQNLV VAVKDNGQPS LSATCSMYLL
ISDNLAEVPE LKDLSYNESN SKLTSYLIIA LVSVSTFFLT FIIIILGLRF CRRRKPRLLF
DGAVAIPSGY LPPNYADVDG TGTLRSTYNY DAYLTTGSRT SDFKFVTSYN DNTLPADQTL
KKSLSDFGDV FGDCNPSPEV GTGVLYSLES AGAAPVVPAG AGHKRQCANL SEGYIKARNW
RISGQRSQVS H
//
