ID A0A3P8PNI3_ASTCA Unreviewed; 809 AA.
AC A0A3P8PNI3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Alpha-macroglobulin receptor-binding domain-containing protein {ECO:0000259|SMART:SM01361};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000018611.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000018611.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000018611.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8PNI3; -.
DR Ensembl; ENSACLT00000019048.1; ENSACLP00000018611.1; ENSACLG00000010860.1.
DR GeneTree; ENSGT00940000162996; -.
DR Proteomes; UP000265100; Chromosome 3.
DR Bgee; ENSACLG00000010860; Expressed in liver.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR CDD; cd02897; A2M_2; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.60.120.1540; -; 1.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR041813; A2M_TED.
DR InterPro; IPR047565; Alpha-macroglob_thiol-ester_cl.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR019742; MacrogloblnA2_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR PANTHER; PTHR11412:SF150; ZGC:171445 PROTEIN-RELATED; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM01419; Thiol-ester_cl; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS00477; ALPHA_2_MACROGLOBULIN; 1.
PE 4: Predicted;
FT DOMAIN 678..768
FT /note="Alpha-macroglobulin receptor-binding"
FT /evidence="ECO:0000259|SMART:SM01361"
SQ SEQUENCE 809 AA; 89565 MW; C78DF8965BC7A207 CRC64;
MDEEACYSFL SPALPPTHIL DRHLHVLAEP NQNWPQYFGP ELFGRYQYLV AIPAVIEAGA
EAKFCATLRQ PSGTLVMTVT LMSREKNTTL FTHTSNEAFQ TCVQFEAPLV QKEVQHFQVE
VRGDTFYSKQ VRKVMIRASD TFTFIQTDKP IYLPGQKGNN VMATVFNYLT SCIMVTVTPG
PSSDYTLTPL SGDLYTSCLC ANERKTLRWT MIPTALGAVN VTVSAEAVAS HVSCDNEVVS
VPDRGRIDVV TKSLIVKVRS PLTEEAEIHL PENVIEGSAR TSVSVLGDIL GRALKNLDGL
LQMPYGCGEQ NMALLAPNIY ILHYLKGTQQ LTAAIMEKAT NFLTSGYQRQ LNYKSADGAY
TTFGTGPGNT WLTAFVVRSF AKAQSFIFID PRKIEESKTW LQHKQQENGC FEKSGKLFNN
GMKGGVSDEV TLSAYVTAAF LEMNTSQHDP VMNKSLACLK ESLSDLSNTY TTALLAYVFT
LAGDVETRAH LLQHLDTVAV REGGFLYWSQ TAAETSASLS VEISSYVLLA KLSASPTAED
LGYASGIIRW LTGQQNYYGG FSSTQDTVVA LQALALYSTL VFSAEGWSTV TVQAPSSQLT
FDVNQGNKLL YQEEALQDVS GKYRLEVKGT ACASVQISAT YNIPTPADVT TLSVKQVCTQ
VSIITLFKHR YSGKEETTNM VILDIKMLSG FSPDPESLKS VSNWTDSTND RVEQKEDHVL
VYIEEVSESH PINHSLEIIQ ELPVDNLKPA VVKIYDYYQP GPSLTKLYSN STLTHFRGSI
RLNSSYKLMF PSVTQRNDTF MFFYHVSVR
//
