ID   A0A3P8PP81_ASTCA        Unreviewed;       443 AA.
AC   A0A3P8PP81;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=RAB3A interacting protein {ECO:0000313|Ensembl:ENSACLP00000018822.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000018822.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000018822.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000018822.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SEC2 family.
CC       {ECO:0000256|ARBA:ARBA00025794}.
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DR   AlphaFoldDB; A0A3P8PP81; -.
DR   Ensembl; ENSACLT00000019263.1; ENSACLP00000018822.1; ENSACLG00000012765.1.
DR   GeneTree; ENSGT00940000157998; -.
DR   OrthoDB; 1361004at2759; -.
DR   Proteomes; UP000265100; Chromosome 17.
DR   Bgee; ENSACLG00000012765; Expressed in testis and 7 other cell types or tissues.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   Gene3D; 1.20.5.4880; -; 1.
DR   InterPro; IPR040351; RAB3IL/RAB3IP/Sec2.
DR   InterPro; IPR009449; Sec2_N.
DR   PANTHER; PTHR14430:SF2; RAB-3A-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR14430; RABIN3-RELATED; 1.
DR   Pfam; PF06428; Sec2p; 1.
DR   SUPFAM; SSF144284; Sec2 N-terminal region; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT   DOMAIN          148..212
FT                   /note="GDP/GTP exchange factor Sec2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06428"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          221..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          122..213
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        23..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        243..262
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  49260 MW;  4FEB7B4636699C56 CRC64;
     MACSSGQNNA ETLEGFHEVN LASPTTPDLQ NQSDQRPAIR HTTPPTSLYR THSLGAPPPG
     LPTSLRADQL PTQPVYSAPR HSHNGSVPGL EAESAEFMSG EDGEECGALS DSLSRLRSPS
     VMEVREKGYE RLKEELAKAQ RELLLKDEEC ERLSKVRDQL GQELEELTAS LFQEAHKMVR
     EANVKQANAE KQLKEALGKI DVLQAEVQAL KTLVLSSPTS PVGELPSVGT GGGVKTPFRK
     GHSRNKSTSS AMLGTQPDPS ATQPIVRECR EVDGQLFSEF KAWKEEPTFD RSCSFLERIY
     REDIYPCLTF NKSELGSAIL EAVEQNTLSV EPVGFQPLPV VKASAVECGG PNGRRSELVT
     KCALSGQTKT CKHRIKFGDS SSYYYVSPYC RYRITAVCNF FTYIRYIHQG LVKQQDAEQM
     FWEVMQLRRE MSLAKLGYYK DQL
//