ID   A0A3P8PQP6_ASTCA        Unreviewed;       582 AA.
AC   A0A3P8PQP6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=ETS domain-containing protein Elk-3-like {ECO:0000313|Ensembl:ENSACLP00000019308.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000019308.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000019308.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000019308.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC       ECO:0000256|RuleBase:RU004019}.
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DR   AlphaFoldDB; A0A3P8PQP6; -.
DR   STRING; 8154.ENSACLP00000019308; -.
DR   Ensembl; ENSACLT00000019753.1; ENSACLP00000019308.1; ENSACLG00000013127.1.
DR   GeneTree; ENSGT00940000157571; -.
DR   OMA; LPSRYPW; -.
DR   OrthoDB; 2884081at2759; -.
DR   Proteomes; UP000265100; Chromosome 20.
DR   Bgee; ENSACLG00000013127; Expressed in ovary and 3 other cell types or tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR046328; ETS_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849; ETS; 1.
DR   PANTHER; PTHR11849:SF178; ETS DOMAIN-CONTAINING PROTEIN ELK-1; 1.
DR   Pfam; PF00178; Ets; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW   Nucleus {ECO:0000256|RuleBase:RU004019}.
FT   DOMAIN          14..94
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          102..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          230..258
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..250
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..460
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   582 AA;  62268 MW;  E2DAB137FAEF91E7 CRC64;
     MESNPLINAM DPSITLWQFL LHLLEDQRQR HLISWTSEDG EFKLLDAEEV ARLWGLRKNK
     HNMNYDKLSR ALRYYYDKNI IKKVSGQKFV YKFVSQPDPS LPDGIRSIEE GQRRDVSDSN
     NQSKSLGGVA PTCPTKGLPQ RSSPSSSQKS SRNDYMKSGL YSTFTIQSLQ ASPNPRPIKS
     ELLLQQEPVP KVDRTPREVC VLPESKSSPS VGSAADSVLQ VIVTQTSPCP TPALSPQIPA
     NSNGQSQNPP AAPLSDPPQI YLTNMGDPST LITLGGGTVS PVPPPHVSMG TQGPQQEDCG
     GLTNPTNFPS HHPHAAPHQS HPAPVFVIIN PPLNQQQQQV PMTTAAPPPS VALPPTARPP
     PIVIKEENLP SEQELLEMVT LDGKRVEEVP QLICDSGEPE PPPTIVESPP PPCIDAGVGV
     QQPAEEERTE GEGQDTLTDP VIPPVTTSLP VTSPAASSSD AVPPKQKKPR GLELPSSPSL
     PPGLSLDKVN AAVNSLLAPG SATNTLTPTV ITSHALTPVL LTPSPLPSTI HFWSTLSPIA
     PRSPAKLSFQ FPSNGSNQIH IPALSVDGLS TPVVLSPGPQ KP
//