ID   A0A3P8PR59_ASTCA        Unreviewed;       293 AA.
AC   A0A3P8PR59;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Synaptoporin {ECO:0000313|Ensembl:ENSACLP00000019384.1};
GN   Name=SYNPR {ECO:0000313|Ensembl:ENSACLP00000019384.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000019384.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000019384.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000019384.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the synaptophysin/synaptobrevin family.
CC       {ECO:0000256|ARBA:ARBA00006476}.
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DR   AlphaFoldDB; A0A3P8PR59; -.
DR   STRING; 8154.ENSACLP00000019384; -.
DR   Ensembl; ENSACLT00000019830.1; ENSACLP00000019384.1; ENSACLG00000013184.1.
DR   GeneTree; ENSGT01030000234637; -.
DR   OMA; ANKCMAV; -.
DR   Proteomes; UP000265100; Chromosome 5.
DR   Bgee; ENSACLG00000013184; Expressed in camera-type eye and 3 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR001285; Synaptophysin/porin.
DR   PANTHER; PTHR10306; SYNAPTOPHYSIN; 1.
DR   PANTHER; PTHR10306:SF16; SYNAPTOPORIN; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR00220; SYNAPTOPHYSN.
DR   PROSITE; PS51225; MARVEL; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        111..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        210..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          25..232
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   REGION          250..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   293 AA;  32472 MW;  8C5440ED29412AC9 CRC64;
     MMEIGIFLFS RLVFAQLVSA GTFQVLKLPL GFIRVLEWLF SIFAFATCGG YTGQLQVSVD
     CMEKASSNLS IGIDFGYPFR LHQVSFEAPM CEAMRRERVF LTGDYSSSAE FFVTIAVFAF
     LYSLTAAIIY IFFLNKYHEN SRAPLIDFVV TVVFSFLWLV SSSAWAKALS DVKVATDPDE
     VQLLISACKD QTNKCGSLHG PRWSGLNTSV VFGFLNFVLW AGNIWFVFKE TGWHKGASRF
     AAGASEKQGG TFSQQSYNQG SFDQSGSYNT QGNMGQPSEY SQVGGPTSYP SQM
//