ID A0A3P8PRP8_ASTCA Unreviewed; 555 AA.
AC A0A3P8PRP8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=DAB adaptor protein 1 {ECO:0000313|Ensembl:ENSACLP00000019750.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000019750.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000019750.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000019750.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8PRP8; -.
DR Ensembl; ENSACLT00000020209.1; ENSACLP00000019750.1; ENSACLG00000013338.1.
DR GeneTree; ENSGT00940000158038; -.
DR Proteomes; UP000265100; Chromosome 23.
DR Bgee; ENSACLG00000013338; Expressed in camera-type eye and 5 other cell types or tissues.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR CDD; cd01215; PTB_Dab; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR048559; DAB1/2_SBM.
DR InterPro; IPR048561; Dab_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR47695:SF4; DISABLED HOMOLOG 1; 1.
DR PANTHER; PTHR47695; PID DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF21792; DAB2_SBM; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782}.
FT DOMAIN 38..179
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..206
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 60194 MW; 2810FC753ED99728 CRC64;
MSTETELQPA VRPSSVRRDS KRKGQDRSET ALIRRFKGDG VRYKAKLIGL DEVTAARGDK
LCQDSMMKLK GIAAAARSKG EHKQKVFLTV SFGGIKIFDE KSGVLQHHHA VHEISYIAKD
ITDHRAFGYV CGKEGNHRFV AIKTAQSAEP VILDLRDLFQ LIYDIKQREE KEKKAQKDKQ
CEQAVYQNGH KRKPHHHHHH HQHHHSHEQP LHQEQTEQQQ QSQSHMIDLD LDMVTQNINQ
LEIFGDMSTP PDITSPSTPA SPANTLDPSQ GLQPPTELFA PFNPASVPSG YVTMGAVPPG
HWSQQAFAAQ TPLAFGVQSP LGPVAQVLPG GQPLIWGQAN IFPATQQQWA AMAAGAFPPT
AYLPAQPVGT LPAAMFQTLT PVTTVTPAGE SHSSTGASAS APSPSASSSP QHGERGKKMG
KEMFKDFQLA KPPAMPSKKA DQPSLTGTSE AFSTYFSRVG TAQDTDDCDD FDISQMNLTP
VTSTTPSTNS PPTPAPRQSS PSKSSASHVS DPPTDATDPP TDDSFGEAEG SPSRSGEEDA
KRKDPLYAQI NKGKK
//
