ID   A0A3P8PST5_ASTCA        Unreviewed;       777 AA.
AC   A0A3P8PST5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Metastasis suppressor protein 1-like {ECO:0000313|Ensembl:ENSACLP00000020140.1};
GN   Name=MTSS1 {ECO:0000313|Ensembl:ENSACLP00000020140.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020140.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000020140.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000020140.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8PST5; -.
DR   Ensembl; ENSACLT00000020602.1; ENSACLP00000020140.1; ENSACLG00000013576.1.
DR   GeneTree; ENSGT00950000183156; -.
DR   Proteomes; UP000265100; Chromosome 11.
DR   Bgee; ENSACLG00000013576; Expressed in liver and 8 other cell types or tissues.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   CDD; cd07643; I-BAR_IMD_MIM; 1.
DR   CDD; cd22060; WH2_MTSS1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   InterPro; IPR003124; WH2_dom.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
DR   PROSITE; PS51082; WH2; 1.
PE   4: Predicted;
FT   DOMAIN          1..254
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   DOMAIN          749..766
FT                   /note="WH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51082"
FT   REGION          259..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          410..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          494..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          535..753
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..320
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..523
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        539..583
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        634..655
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        710..736
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   777 AA;  84309 MW;  9BF45633FB682C29 CRC64;
     MEAVIEKECS ALGGLFQTVI GDMKSSYPIW EDFITKAGKL QSQLRATVVA VAAFLDAFQK
     VADLATNSRG GTRDIGSALT RMCMRHRSIE AKLKQFSTGF LEGLINPLQE QMEEWKRGVN
     TLDKDHAKEY KRARQEIKKK SSDTLKLQKK AKKADNFGRG DIQPQLDSAM QDVSDKYILL
     EETEKQALRK ALIEERQRFC CFVAMLRPIV DEEISMLGEV THLQTISEDL KALTSDPHKL
     PPASEQVILD LKGSDYGWSY QTPPSSPSTT MSRKSSMCSS TLPQQTPARL PSISSHDSGF
     ISSSQDQYTL SKSSSPLPAE KKLSNGFDHY SPASSPYLHS NGGSLGSVSN TAFPFFPPSS
     STSTSCPTRS WSRPASALLP DYPPYCTLGS PMMPSSRVPS WKDWAKPGPY DQPMVNTLRR
     KKDKESPAVV DSNGSMNCDN SPPSAQTAAP AALQTPSQSA LVQDKNRNTP AAVRAGDIEA
     QDDLALALSR GLELDTQRSS RDSIQCSSGY STQTNTPCCS EDTIPSQVSD YDYFSMAGDP
     ESEQQQSDFD KSSTIPRNSD ITQSYRRMFQ AKRPASTAGL PSSQVPYPGP GAYHTGPYPP
     TPIHTGAYAS TPTAQYPPTP TGHGPVIVTP GVATIRRTPS SKPSGRRSGS VTGTGPIPIR
     TPVVPVKIPT VPDMPGAVNG NRGEEMVGRE ESPSSPTFTG EEDPGTLPMA SWSGQATTNP
     PNLPNYVSQQ HLQSEMRQEG GGDDSGEQEE GDMLMAIRKG VKLKRTFTND RSAPRIA
//