ID A0A3P8PT44_ASTCA Unreviewed; 629 AA.
AC A0A3P8PT44;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020197.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000020197.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000020197.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR AlphaFoldDB; A0A3P8PT44; -.
DR Ensembl; ENSACLT00000020661.1; ENSACLP00000020197.1; ENSACLG00000013247.1.
DR GeneTree; ENSGT00940000164201; -.
DR Proteomes; UP000265100; Chromosome 5.
DR Bgee; ENSACLG00000013247; Expressed in spleen and 2 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932}.
FT DOMAIN 44..317
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 536..627
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
SQ SEQUENCE 629 AA; 71193 MW; C93D5D88D4F316EB CRC64;
LASTVLGLLS PSELMSTLNQ QYDEKVRPLI DLIDSLRSLG VEKDLALPAI AVIGDQSSGK
SSVLEALSGV ALPRGSGIVT RCPLELKMTK TKEGEAWYGK ISYRDFEEKI KEPAVVEKMI
REAQLKLIGN EMGISSELIS LEIASPDVPD LTLIDLPGIA RVAVDGQSAD IGDKIKTIIQ
TVISKQETIN LVVVPCNVDI ATTEALNMAK LVDPDGERTL GVLTKPDLVD KGTEENVVKI
VHNEVIPLKK GYMVVKCRGQ KEITEKVSLS EALKNEEAFF KEHAHFQTLF DEGKASVPKL
AEKLTLILVH HIQKSLPRLD EQTHKKLEQT QENLKKLRTG PPSDATQRQK FLSDLVLAFA
QDAISLTKGE ELKCGYNSSI FFTLRNKFEA WEKIIKDSAS SFKEHILREE SQFERTYRGR
ELPLFVSYST FESIIQKQIK QLEEPAIQKL KEVSEVVRKE LFELAQNSFV GFPNLINTAK
MNIETIRNER EEEAKPILGM QFKMEMLVYT QDSKYITEIR NGISKYGQLY FGGMTSKEMM
RHFEAYYNIV GQRLADQIPL VIRYQMLQEF ASELQSKMLD AFLDKERKEH LLQEDSGTKN
KREDLKKRLE RLSQAHILLS DIQNFQPDS
//
