ID A0A3P8PT66_ASTCA Unreviewed; 1072 AA.
AC A0A3P8PT66;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Dishevelled associated activator of morphogenesis 1 {ECO:0000313|Ensembl:ENSACLP00000020271.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020271.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000020271.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000020271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8PT66; -.
DR Ensembl; ENSACLT00000020740.1; ENSACLP00000020271.1; ENSACLG00000013675.1.
DR GeneTree; ENSGT00940000156452; -.
DR Proteomes; UP000265100; Chromosome 15.
DR Bgee; ENSACLG00000013675; Expressed in anal fin and 8 other cell types or tissues.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45725:SF16; DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1; 1.
DR PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 51..426
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 606..1002
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1020..1052
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 531..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1042..1072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 444..527
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 535..600
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 982..1024
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1042..1059
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1072 AA; 122186 MW; 5C4EC507FF965EFE CRC64;
MPPRKRGGGS GGGGGRSGFS AIFCCFNNRD HPEITYKLRD DFALQSMEPS LPMPGNDELD
SMFAELVDEL DLTEKHREAM FALPAEKKWQ IYCSKKKEQE ENKSATSWPE YYIDQLNSMA
ARKTLLALEK EDEEERNKTI ENLKTALRTQ PMRFVTRFID LDGLTCILNF LKSMDYDTTE
SQIHTSLIGC IKALMNNSQG RAHVLAHSES INIIAQSLAT ENIKTKVAVL EIMGAVCLVP
GGHKKILESM LHYQRFACER TRFQTLVNDL DRSTGRYRDE VSLKTAIMSF INAVLSQGAE
ETSLEFRIHL RYEFLMLGIQ PVIDKLHSHE NATLDRHLDY FEMLRNDDEL AVSKRFESVH
VDTKSATQVF DLIRKKMSHT DAYPHFMSVL HHCLLMPHKR SGNTVQYWLL LDRIVQQMVL
QNDKGHDPDV TPLENFNVKN VVRMLVNENE VKQWKEQAEK MRKEHHELQQ KFEKKERECD
AKTQEKEDMM QTLNKMKEKL EKESNEQKNV KQQVAELTAR LHELSTRQAA VVPGGPPVAP
GPPGGPVPQP GFAGIAPPPP PPPGGMMPPP PPPPPPPGGP PPPPGLPPIG GIPPPPGAPL
GSSLKKKNIP QPSNPLKSFN WSKLAENKLE GTVWMEVDDA KVFKVLDLDD IEKTFSAYQR
QQKEAEDDTL GSKKVKELSV IDGRRAQNCN ILLSRLKLSN DEIKRAILTM DEQEDLPKDM
LEQLLKFVPE KSDVDLLEEH KHELDRMAKP DRFLYEMSRI NHYQQRLQSL YFKKKFAERI
AEIKPKVEAL GKASKEVLNS RNLKQLLEVV LAFGNYMNKG QRGNAYGFKV SSLNKIADTK
SSIDKNITLL HYLITILEKK YPKVLKFQED LQSISEAAKV NMTELEKDIG NLRSGLKSVE
SELEYQKKGP QEPGDKFVSV VSQFITVASF SFTDVEDSLI EAKELFLRAV KHFGEDASKM
QPDEFFGIFD QFLQSFTEAQ QENENIRKRK EEEERRAKVE AQLREQREKE RKARKAKANG
EEDGGEFDDL VSALRSGEVF DKDLSKMKRN RKRINNQNTD SGRERPVTKL NF
//
