ID A0A3P8PTF2_ASTCA Unreviewed; 395 AA.
AC A0A3P8PTF2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Carbohydrate sulfotransferase {ECO:0000256|RuleBase:RU364020};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU364020};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020258.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000020258.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000020258.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU364020}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323,
CC ECO:0000256|RuleBase:RU364020}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006339, ECO:0000256|RuleBase:RU364020}.
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DR AlphaFoldDB; A0A3P8PTF2; -.
DR STRING; 8154.ENSACLP00000020258; -.
DR Ensembl; ENSACLT00000020727.1; ENSACLP00000020258.1; ENSACLG00000013764.1.
DR GeneTree; ENSGT00940000159167; -.
DR OMA; KYTDPME; -.
DR Proteomes; UP000265100; Chromosome 17.
DR Bgee; ENSACLG00000013764; Expressed in brain.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR InterPro; IPR018011; Carb_sulfotrans_8-10.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12137; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12137:SF32; CARBOHYDRATE SULFOTRANSFERASE 11; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU364020};
KW Glycoprotein {ECO:0000256|RuleBase:RU364020};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364020};
KW Membrane {ECO:0000256|RuleBase:RU364020};
KW Signal-anchor {ECO:0000256|RuleBase:RU364020};
KW Transferase {ECO:0000256|RuleBase:RU364020};
KW Transmembrane {ECO:0000256|RuleBase:RU364020};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364020}.
FT TRANSMEM 58..77
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364020"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 395 AA; 45879 MW; 845A793A6A729EFF CRC64;
MLDVFSSLTG GQSSSVPPEP RSLRQTGPSF PHKARGILQP LRPAMKQTLS ELMRMSRICR
MIFATCLGSF ILVIFYFQSM FQPVMRRNPF MVEGCCRKGS RNALQELYNP TQTELSGAAV
LHQARRDQVV DACRVYSASS RKRRVLTPGD LKHLVVDEDH ELIYCYVPKV ACTNWKRVMM
VLTGRGKYSD PMEIPSNEAH VPSNLKTLNQ YSIAEINHRL KNYLKFLFVR EPFERLVSAY
RNKFTLKYNS SFHKRFGTRI IRRYRKNATQ DALLNGADVK FKEFIEYLVD PATQRDGLNE
HWQTVYQLCH PCHIHYDMVG KYETLEEDAN YLLQLVGVGD SLRFPTYAKS TRTTDAMTAQ
FFSNISTQQQ IQLYQLYKLD FLMFNYSIPS YLRLE
//
