ID   A0A3P8PU36_ASTCA        Unreviewed;       304 AA.
AC   A0A3P8PU36;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Adenosine deaminase domain containing 1 (testis-specific) {ECO:0000313|Ensembl:ENSACLP00000020570.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020570.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000020570.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000020570.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8PU36; -.
DR   STRING; 8154.ENSACLP00000020570; -.
DR   Ensembl; ENSACLT00000021044.1; ENSACLP00000020570.1; ENSACLG00000013974.1.
DR   GeneTree; ENSGT00940000156842; -.
DR   OMA; KESIFCM; -.
DR   Proteomes; UP000265100; Chromosome 2.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd19905; DSRM_ADAD1; 1.
DR   Gene3D; 3.30.160.20; -; 1.
DR   InterPro; IPR002466; A_deamin.
DR   InterPro; IPR044455; ADAD1_DSRM.
DR   InterPro; IPR014720; dsRBD_dom.
DR   PANTHER; PTHR10910:SF103; ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR   Pfam; PF02137; A_deamin; 1.
DR   Pfam; PF00035; dsrm; 1.
DR   SMART; SM00552; ADEAMc; 1.
DR   SMART; SM00358; DSRM; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR   PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR   PROSITE; PS50137; DS_RBD; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          9..77
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          135..304
FT                   /note="A to I editase"
FT                   /evidence="ECO:0000259|PROSITE:PS50141"
SQ   SEQUENCE   304 AA;  33870 MW;  1073B5C4107BD42A CRC64;
     ARYRNGETNA ISLLHQLAQT LQFHLEMKET VAPASTTGLY FAFCAVIDGV QYKTGIGVTK
     KEARLNAAEL AFQDLQPTLE SLKSALPEPF VNLQIPHAVR DQLTKLMNSH PEFSGCAVTT
     AAFLLQTSNG YEVVALGTGN FNTKESISSN GRIVHDSHAV VTARRSLMRF LYRHLLMFFS
     KNANLTQKSI FQQSSSSSFL SLKSGITLHL YVNQLPKGAA QIPSKLRLNP LSMSAWQVNN
     EISLHLSVEG KVLFNFFYLI KVYFLLKVMS TTDKITQWQV LGYQGALLSH FIEPIYVHSI
     LIGK
//