ID A0A3P8PUG2_ASTCA Unreviewed; 557 AA.
AC A0A3P8PUG2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM21-like {ECO:0000313|Ensembl:ENSACLP00000020544.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020544.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000020544.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000020544.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8PUG2; -.
DR STRING; 8154.ENSACLP00000020544; -.
DR Ensembl; ENSACLT00000021018.1; ENSACLP00000020544.1; ENSACLG00000013973.1.
DR GeneTree; ENSGT01040000240400; -.
DR OMA; HWDINEP; -.
DR Proteomes; UP000265100; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19802; Bbox1_TRIM8-like; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF32; BLOODTHIRSTY-RELATED GENE FAMILY, MEMBER 22-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 15..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 149..189
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 348..543
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 190..296
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 557 AA; 63239 MW; A28125A7BC3B1DCC CRC64;
MSAANNLRSE NQFLCSICLD VFTDPVTTSC GHNFCKTCIS QHWDMNVICK CPLCKETFYT
RPQLRVNTFI SEIVAQFRRE AQQKASSSSS EQQAAKPGEV PCDVCTGTRL KALKSCLVCQ
TSYCQTHLEP HLTVKRLKRH QLVDAVENLE GRMCMKHDKL LELFCKTDQT CVCMLCSALD
HKNHEFVPLR EEYEGKKAEL EKTEAEIQQM IQKRRLKIQE ITESVKMSKD AADRQKAEGV
QVFTALMESV ERRLKELMKE IEDKQEATEK QAEGLIKDLE QEISELMERS SEVEQLSRSE
DHLHLLQSFS SLKAASPTKD WTEVRVRPPS YEGTVVRAVE TLEETLWKDM NELFEAELQR
VQQYAVDVSL DPDTAHPYLI LSDDGKQVKY GDVKKKLPDN PERFSPCPNV LGEQSFSSGR
FYFEVQVKGK TKWDLGVARE SINRKGNITL SPQDGFWIVR LRNGNKYSAC ASPPVRLCLH
PGPEKVGVFV DYEEGLVSFY DVGAAALIYS FTGCSFTHKL HPYFCPSNND GGKNSAPLII
SHRVNRVLLC EVAIKPN
//
