ID A0A3P8PUJ5_ASTCA Unreviewed; 283 AA.
AC A0A3P8PUJ5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Voltage-dependent anion-selective channel protein 1 {ECO:0000256|ARBA:ARBA00017554};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020736.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000020736.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000020736.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC raft {ECO:0000256|ARBA:ARBA00004314}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004314}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin family.
CC {ECO:0000256|ARBA:ARBA00007780}.
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DR AlphaFoldDB; A0A3P8PUJ5; -.
DR Ensembl; ENSACLT00000021212.1; ENSACLP00000020736.1; ENSACLG00000014054.1.
DR GeneTree; ENSGT00950000182869; -.
DR OMA; WSNANNL; -.
DR Proteomes; UP000265100; Chromosome 10.
DR Bgee; ENSACLG00000014054; Expressed in brain and 8 other cell types or tissues.
DR GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0008308; F:voltage-gated monoatomic anion channel activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd07306; Porin3_VDAC; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR001925; Porin_Euk.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR PANTHER; PTHR11743; VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL; 1.
DR PANTHER; PTHR11743:SF13; VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1; 1.
DR Pfam; PF01459; Porin_3; 1.
DR PRINTS; PR00185; EUKARYTPORIN.
DR PROSITE; PS00558; EUKARYOTIC_PORIN; 1.
PE 3: Inferred from homology;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023114};
KW Membrane {ECO:0000256|ARBA:ARBA00022452};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Porin {ECO:0000256|ARBA:ARBA00023114};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022452};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00023114}.
SQ SEQUENCE 283 AA; 30634 MW; 8731EC247C28DC66 CRC64;
MAVPPTYADL GKSARDVFTK GYGFGLIKLD LKTKSENGLE FTSTGSANTE TSKVAGSLET
KYKWAEHGLT FTEKWNTDNT LGTEITIEDQ VMYNNVNLYF FPLQSPGSKK GGKLKTGYKC
EHINVGCDVN YDINGTAIHG AAVVGYEGWL AGYQMTFEAG RNRITQSNFA VGYKTNEFQL
HTNVNDGTEF GGSIYQKVND KLETAVNLAW TAGNSNTRFG IAAKYQIDPD ASFSAKVNNS
SLVGLGYTQT LKPGIKLTLS ALLDGKNINA GGHKLGLGLE FQA
//
