ID A0A3P8PVE1_ASTCA Unreviewed; 868 AA.
AC A0A3P8PVE1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Scm like with four mbt domains 2 {ECO:0000313|Ensembl:ENSACLP00000020968.1};
GN Name=SFMBT2 {ECO:0000313|Ensembl:ENSACLP00000020968.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000020968.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000020968.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000020968.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8PVE1; -.
DR Ensembl; ENSACLT00000021446.1; ENSACLP00000020968.1; ENSACLG00000014262.1.
DR GeneTree; ENSGT00940000158123; -.
DR Proteomes; UP000265100; Chromosome 17.
DR Bgee; ENSACLG00000014262; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20118; MBT_SFMBT2_rpt4; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR047355; MBT_SFMBT2_rpt4.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF62; SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2; 1.
DR Pfam; PF02820; MBT; 4.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 4.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS51079; MBT; 4.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 41..141
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 156..261
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 271..377
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 385..482
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 532..646
FT /note="SLED"
FT /evidence="ECO:0000259|Pfam:PF12140"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 98083 MW; 625F11AE212AA571 CRC64;
MQSHTQEQPL ALTTVKPHYP TNGKEEEVNT DADSMEEEVE FNWEEYLEEN GADAAPHTNF
KHVEISLQSS FQPGMKLEVA NKSNPDTYWV ATIITTCGQL LLLRFSGYGE DRKADFWCDV
MTAELHPVGW CAQNNKTLMP PEDNIYLRKA IKEKHSDWTE FLIQDLTGAR TAPANLLEGP
LRGKNTVDLI VDGSVLELQD LLDPYLYWPV RVIQNVGGRL RLRYAGLSEE YHDHDTWLFY
LDVRLRPLGW AQENCLTLEP PTELRSTKST SDWQQALEDA QLDGQKNPLP LEVFKDHVDL
PKHSFKMGMK LEMVSPWEQL QICPVSVTKV YNEFYFQVML DDLSAEAKPH FVVCHANSPG
ILPVQWCMKN GVGLERPRAY EGQDFDWADY LKQSGTEAAP DACFPDTWQS RDFAKDMWLE
AVNPHRPAEV CVAQVTQVRG RLLWLRLEGV PKPLSECIVD VESMDIFPVG WCEANAYPLT
PPIKPVCQKQ KKIAVVQPEK QLARSQPVEA SPVNHYQPAA LDPGSANGRY CCSKIFVNHR
CFSGPYLNKG RIAELPQAVG PGKCTLVLKE LLSMLINAAY KPGRVLKELQ ELEDQSWDCQ
EETLKAKYKG KTYRSTIRIV RLADQIPDFC RKVCVKLQCC PNLFSPILVT DKCPENCSVQ
TKTKYTYYYG KKRKLSKPTA GEETAEGELA KPTRRRKKRK AIFVQKKRRS SAVDYTPAGS
PQDSDEGEED EERALQSGSE GTSSEPREDH TDTSSVEVTS SRPRRATALR RAVSAGNPAL
GPALSPEAPA GRRRSTRSLS AYNQNSKYQP AKGQDMQVEE EDGQLVLDRN PLEWSVDEVV
QFINSTDCAS LAGIFQEQVN KKQKHNYC
//
