ID   A0A3P8PZE8_ASTCA        Unreviewed;       571 AA.
AC   A0A3P8PZE8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Inositol polyphosphate-5-phosphatase Ka {ECO:0000313|Ensembl:ENSACLP00000022398.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000022398.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000022398.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000022398.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC       type II family. {ECO:0000256|ARBA:ARBA00005910}.
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DR   AlphaFoldDB; A0A3P8PZE8; -.
DR   STRING; 8154.ENSACLP00000022398; -.
DR   Ensembl; ENSACLT00000022921.1; ENSACLP00000022398.1; ENSACLG00000015203.1.
DR   GeneTree; ENSGT00940000156538; -.
DR   OMA; NSECQHI; -.
DR   Proteomes; UP000265100; Chromosome 14.
DR   Bgee; ENSACLG00000015203; Expressed in camera-type eye and 7 other cell types or tissues.
DR   GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   CDD; cd09094; INPP5c_INPP5J-like; 1.
DR   Gene3D; 2.60.40.2840; -; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR046985; IP5.
DR   InterPro; IPR000300; IPPc.
DR   InterPro; IPR041611; SKICH.
DR   PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR   PANTHER; PTHR11200:SF117; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K; 1.
DR   Pfam; PF17751; SKICH; 1.
DR   SMART; SM00128; IPPc; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   3: Inferred from homology;
FT   DOMAIN          110..438
FT                   /note="Inositol polyphosphate-related phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00128"
SQ   SEQUENCE   571 AA;  66129 MW;  8B24FAFC8273083D CRC64;
     MEDSEEPLES HQLYLGEKEE ESFSRLKQAS QFWTRMDEIT RLLGSIERKR TESVSTQSTG
     SKLALLHRLH QLMTCVEDLN PKNELHEKVV KTLDYAFLVC GKRANKPKKD SFRLHMVTWN
     VATADPPDDV TTLLHLNSPK SPDLYVIGLQ EVYSGPLRFV SDAVFDDPWS YLLMSLLAPQ
     KYIKVSSIRM QGLLLLFFSK LEHVPFIRDV QATYTRTGLF GYWGNKGGVS IRLSFYGHTL
     CFLNCHLAAH MNYASERVDE FEYIMDMQSF DCKRAPAIVD HRLVFWFGDL NFRIQDHGMH
     FVRTCIDKQN YSLLWSKDQL IMMKQKEQVL QEFEEGPLDF QPTYKFDRSS DTYDTSAKKR
     KPAWTDRILW RLRPKALPPD EENENKVGLD AKKLKQLEED MEYPLKIRQD VYTSMMEYSI
     SDHKPVIGIF TLELRKMYET PLVRLRAEGD WSADIDAMVV YSPLQPFPSS TWDWIGLYKV
     GFSSVSDYIT YTWVKDDEVA FNEEVIQVYV SKEEIPVQGG DCVLCYYCNA LKCIIGISEP
     FQVQASKVAI EEGMLPERIN GLDKAVSGDD F
//