ID   A0A3P8Q0N7_ASTCA        Unreviewed;       912 AA.
AC   A0A3P8Q0N7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Exocyst complex component 1 {ECO:0000313|Ensembl:ENSACLP00000022828.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000022828.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000022828.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000022828.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SEC3 family.
CC       {ECO:0000256|ARBA:ARBA00006518}.
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DR   AlphaFoldDB; A0A3P8Q0N7; -.
DR   Ensembl; ENSACLT00000023365.1; ENSACLP00000022828.1; ENSACLG00000015314.1.
DR   GeneTree; ENSGT00940000158640; -.
DR   Proteomes; UP000265100; Chromosome 23.
DR   Bgee; ENSACLG00000015314; Expressed in testis and 7 other cell types or tissues.
DR   GO; GO:0000145; C:exocyst; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   CDD; cd14683; PH-EXOC1; 1.
DR   Gene3D; 2.30.29.90; -; 1.
DR   InterPro; IPR028258; Sec3-PIP2_bind.
DR   InterPro; IPR048628; Sec3_C.
DR   InterPro; IPR019160; Sec3_CC.
DR   PANTHER; PTHR16092:SF14; EXOCYST COMPLEX COMPONENT 1 ISOFORM X1; 1.
DR   PANTHER; PTHR16092; SEC3/SYNTAXIN-RELATED; 1.
DR   Pfam; PF15277; Sec3-PIP2_bind; 1.
DR   Pfam; PF20654; Sec3_C-term; 1.
DR   Pfam; PF09763; Sec3_CC; 1.
DR   SMART; SM01313; Sec3-PIP2_bind; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          31..122
FT                   /note="Exocyst complex component Sec3 PIP2-binding N-
FT                   terminal"
FT                   /evidence="ECO:0000259|SMART:SM01313"
FT   REGION          568..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          227..261
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   912 AA;  104453 MW;  F3E75C2B72817487 CRC64;
     MTAIKHALQR DIFTPNDERL LGIVNVCKAG KKKKNCFLCA TVTTERPVQV KVVKVKKSDK
     GDFYKRQQTW ELRDLTEVDA KDASKENPEF DLHFEKVYRW VASSTAEKNS FISCIWKLNQ
     RYLRKKVEFV NVSSQLLEEL PKAEESVPSG ESQSVAGGDE DALDEYQELS TREEQDIESM
     MVTCEYAISN AEAFAEKLFK ELQVLDGANI QSIMASEKQV NILMQLLDEA LGEVDTIEGK
     LSSYEEMLQS VKEQMDQISQ SNRLIQISNT NNGKLLDEIQ FLVNYMDLSK GHIRALQEGD
     LTSPKGIEAC INASEALLQC MNVALRPGHE KLMAVNQQQL LFAELRDTFA RRLTNHLNNV
     FVHQFNHFSH FKMTIPQFYR SSCLSLPGHD QSSTLSQHTA ELTLPKHSPL HRDLLRYAKL
     MEWLKNTHRE KYEGLSRTYV EYMSKLYERE IKEFFEVAKI KMAGTSKDPK GKFGLHGSSG
     KLTGSTSSLN KLTVQGSNSR RSQSSSLLDM GNMSASDLDV ADRTKFDKIF EQVLSELEPL
     CLAEQDFISK FFKLQQHLTV APPLAQPEAE DFDGSLPSKK PPQAEHKHSL SSEKDIVRLM
     MNKIFQSIET ELNSLIALGD KIDSFHSLYM LVKMSHHVWT AENVDPASYL STTLGNVLVT
     VKRNFDKCIS NQIRQMEEFK ISKKSKVGIL PFVTGFEEFA ELAETIFRNA ERRGDLDKAY
     VKLIRAVFMN VEKVANESQK TPRDVVMMEN FHHIFSTLSR LKISCLDAER REAKHKYTDH
     LQSYVINSLG QPLEKLNHFF EGVEARVAQG VREEEVSYQL AFNKQELRKV IKEYPGKEVK
     KGLDNLYKKV DKHLCEEESL LQVVWHSMQD EFIRQYKHFE DLIGRCYPGS GITMEFTIQD
     MLEYFSSIAQ SH
//