ID A0A3P8Q1F9_ASTCA Unreviewed; 718 AA.
AC A0A3P8Q1F9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=MBT domain-containing protein 1-like {ECO:0000313|Ensembl:ENSACLP00000022894.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000022894.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000022894.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000022894.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3P8Q1F9; -.
DR STRING; 8154.ENSACLP00000022894; -.
DR Ensembl; ENSACLT00000023439.1; ENSACLP00000022894.1; ENSACLG00000015503.1.
DR GeneTree; ENSGT00940000153840; -.
DR OMA; GLPFRWF; -.
DR OrthoDB; 5405166at2759; -.
DR Proteomes; UP000265100; Chromosome 4.
DR Bgee; ENSACLG00000015503; Expressed in anal fin and 7 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20126; MBT_MBTD1_rpt3; 1.
DR CDD; cd20129; MBT_MBTD1_rpt4; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 3.30.60.160; -; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247:SF79; MBT DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR Pfam; PF02820; MBT; 4.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00561; MBT; 4.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS51079; MBT; 4.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 79..114
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT REPEAT 173..277
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 285..371
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 373..488
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 496..592
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..627
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..667
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 718 AA; 79485 MW; 7258D936656D5678 CRC64;
MENPRDLVER QSRKRRDSFG MLDGLDEDRS SCSTESSGGS GASSPEDSED EELGGGVTQL
NPSSSLTLIK TNGQVYTYPD GKAGMATCEM CGMVGVRDAF YSKTKRFCSV SCSRSYSSNS
KKASILARLQ GKPPTKKAKV LQKQPLMTKL AAYAQQQANQ QGGVKKSVSM ELFDWGRYLG
DGDVMGAPVS CFQHVPMGNS WGGISEGIRV EVPNTDSGLP MKVYWIAGII KLAGFKALLR
YEGFDCDSTR DFWLNLCVPD IHPVGWCAAG GKPLVPPQSI LHRFSNWKTF LIKRLTGSKT
LPPDFASKVQ ESMQFPFKKQ MRVEVVDKTH LCRTRVALVE QVIGGRLRLV YEECDDGTDD
FWCHMYSPLI HSIGWSRSIG HRFKRSDVSK KLDGQMDAPG QLFAKVKEVD QSGRWFEDGM
KLEAIDPLNL SAICVATVRK VLADGYLMIG IDGSEAADGS DWFCYHSTSP SIFPAGFCEI
NNIELTPPRG YSSLPFRWFE YLKESKSVAA PVNLFNRDVP NHGFRPGMKL EAVDLMEPRL
VCVATVTRIV HRLLRIHFDG WEDEYDQWVD CESPDLYPVG WCQLTGYQLQ PPAVNAGSRD
LQSAASRQRK KSQQYKGQKK KRKLPIAKRP VSLSGTMVTG VPRSLSGDEN ETPPDYPSPP
PPASAAQPPS ANLESSPRTE GGAGVREENA RAPELSSHRT EAETHRSSAD FLSSRDQQ
//
