ID A0A3P8QAB1_ASTCA Unreviewed; 204 AA.
AC A0A3P8QAB1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Interleukin 17D {ECO:0000313|Ensembl:ENSACLP00000026077.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000026077.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000026077.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000026077.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-17 family.
CC {ECO:0000256|ARBA:ARBA00007236}.
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DR AlphaFoldDB; A0A3P8QAB1; -.
DR STRING; 8154.ENSACLP00000026077; -.
DR Ensembl; ENSACLT00000026696.1; ENSACLP00000026077.1; ENSACLG00000017743.1.
DR GeneTree; ENSGT00940000161739; -.
DR OMA; YDPKRYP; -.
DR OrthoDB; 4208634at2759; -.
DR Proteomes; UP000265100; Chromosome 16.
DR Bgee; ENSACLG00000017743; Expressed in anal fin and 6 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020440; IL-17_chr.
DR InterPro; IPR010345; IL-17_fam.
DR Pfam; PF06083; IL17; 1.
DR PRINTS; PR01932; INTRLEUKIN17.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..204
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018157600"
FT REGION 183..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 204 AA; 23213 MW; DFD682C88A6989B3 CRC64;
MPHRVHVLLL LLLSLCRPAA ATRVRNKTVR TRSCLDMPEE KLEEIFGRLS VGVMSAFHHA
LQLEPQDKLN LTCPTTARVP TDGKTRLPVN LLSISPWAYR ISYDPKRYPR YIPEAYCLCK
GCLIRPYGEE SSQYRSTLVY APSVILRRTG SCVGGRHSYT EIYVSIAVGC TCVPLLEKRP
KKSNQSLQRR EPKARKLFTP RKEA
//
