ID   A0A3P8QAJ8_ASTCA        Unreviewed;       591 AA.
AC   A0A3P8QAJ8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Cell division cycle 23 {ECO:0000313|Ensembl:ENSACLP00000026525.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000026525.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000026525.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000026525.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8QAJ8; -.
DR   Ensembl; ENSACLT00000027147.1; ENSACLP00000026525.1; ENSACLG00000017972.1.
DR   GeneTree; ENSGT00950000182950; -.
DR   Proteomes; UP000265100; Chromosome 10.
DR   Bgee; ENSACLG00000017972; Expressed in testis and 8 other cell types or tissues.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR007192; APC8.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR   PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR   Pfam; PF04049; ANAPC8; 1.
DR   Pfam; PF13414; TPR_11; 1.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 3.
PE   4: Predicted;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          15..253
FT                   /note="Cdc23"
FT                   /evidence="ECO:0000259|Pfam:PF04049"
FT   REPEAT          246..279
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          316..349
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          350..383
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   591 AA;  68500 MW;  D077F4841972A92C CRC64;
     MKMAALCSEF GDLLQIKKQL ISVISLCKER GLLHSAKASE LAFALDPLPK DELPPTSPLT
     EEDAQDLDAL TLAKSYFDLK EYDRAAYFLK GCRSQKAYFL YMYSRYLSGE KKKDDETVDS
     LGPLEKGQVR NEALRELRVE LSKKHTAGEL DGFTLYLYGV VLRKLDLPKE AVDVFVEGIH
     ALPLHWGAWL ELSNLVTNIE MLKSLSLPDC WIKDFFMAHM YTELQMIKEA LQKYQNLIEA
     GFSKSTYIIS QIAVAYHNIR DIDQALALFN ELREQDPYRI DNMDTFSNLL YVKSMKPELS
     YLAHNLVEID KGHRLQEDVT YASNYYSLRS QHEKAALYFQ RALKLNPRCL GAWTLMGHEY
     MEMKNTSAAI QAYRHAIEVN KRDYRAWYGL GQTYEILKMP FYCLYYYRKA HQLRKLIHIY
     KHLLFFFLRP NDSRMLVALG ESYEKLSQQA EAKKCYWRAY SVGDVEKMAL LKLAKLHEQL
     NESDDAAQCY MLYIQDIFSC GEQLEHAEVS TALRYLGQYY FKNKLYDEAS LCAQRCCDYN
     DAREEGKALL RQISQVRDQI ETPSADLFAP LSNNNTPVRR VSPLNLISFT P
//