ID   A0A3P8QB88_ASTCA        Unreviewed;       606 AA.
AC   A0A3P8QB88;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Cationic amino acid transporter 2-like {ECO:0000313|Ensembl:ENSACLP00000026790.1};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000026790.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000026790.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000026790.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3P8QB88; -.
DR   Ensembl; ENSACLT00000027420.1; ENSACLP00000026790.1; ENSACLG00000018154.1.
DR   GeneTree; ENSGT00940000164978; -.
DR   Proteomes; UP000265100; Chromosome 10.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 2.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR029485; CAT_C.
DR   PANTHER; PTHR43243:SF19; AA_PERMEASE_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   Pfam; PF13906; AA_permease_C; 1.
DR   PIRSF; PIRSF006060; AA_transporter; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        37..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        191..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        381..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        490..511
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        523..543
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        549..567
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          522..572
FT                   /note="Cationic amino acid transporter C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13906"
SQ   SEQUENCE   606 AA;  65765 MW;  6CAE2E7AE5CD8A88 CRC64;
     MSGAKVLQFL QNISRRKPLE PEGEVSNFRR CLTTLDLVAL GVGSTLGAGV YVLSGEVARA
     VAGPSIIISF LIAAVASIFA GLCYAEFGAR VPKTGSAYLY SYVTVGEIWA FVTGWNLLLS
     YVIGTSSVAR AWSGTFDDLI GNVIANSLGK QVAMDLPGLA PYPDFFAAGI IMLLAGILAF
     GVKESATVNK VFTAVNILVL LFVILSGFIK GDINNWYRYE DTLPNQSENY TTLNKTTTYG
     SGGFFPFGFE GTLAGAATCF YAFVGFDCIA TTGEEVQNPQ KSIPLGIVAS LLICFLAYFG
     VSATLTLLMP YYLLSVHSPL PVAFTYIGWG PAKYAVAVGS LCALSTSLLG SMFPMPRVLF
     AMARDGLLFR PLSNMSDRQS PVIATLASGV VAAIMALLFD LKSLVDMMSI GTLFAYTLVA
     ICILILRYQT DLSDDSSLSK AEPFTIGGIL CPPYQATTRT SKNVSLLTFV IIVLSVFVSE
     AVDYLQALEW WSILCLSVIV AMIFLIILIV WRQPQNTAEA AFMVPFVPLL PIFSTFVNVH
     LMAQLGSDTW IRYTVWMGVG LIIYFCYGVR HSVQKQRLSH LDTKSESQDG LDMCRRGMVD
     TLDKRC
//