ID A0A3P8QBG8_ASTCA Unreviewed; 524 AA.
AC A0A3P8QBG8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Fibroblast growth factor receptor substrate 2-like {ECO:0000313|Ensembl:ENSACLP00000026676.1};
GN Name=FRS3 {ECO:0000313|Ensembl:ENSACLP00000026676.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000026676.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000026676.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000026676.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8QBG8; -.
DR Ensembl; ENSACLT00000027303.1; ENSACLP00000026676.1; ENSACLG00000018111.1.
DR GeneTree; ENSGT00940000159495; -.
DR Proteomes; UP000265100; Chromosome 5.
DR Bgee; ENSACLG00000018111; Expressed in ovary and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01202; PTB_FRS2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR038742; FRS2_PTB.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR PANTHER; PTHR21258:SF39; FIBROBLAST GROWTH FACTOR RECEPTOR SUBSTRATE 3; 1.
DR Pfam; PF02174; IRS; 1.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51064; IRS_PTB; 1.
PE 4: Predicted;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Myristate {ECO:0000256|ARBA:ARBA00022707}.
FT DOMAIN 13..115
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 205..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 59046 MW; 4718B5C1780B2878 CRC64;
MGSCWSCLYR DPIRDNHLTK FKVTNVDDEG NELGSGIMEL TQTELILHTR KRDAIRWPYL
CLRRYGYDSN LFSFESGRRC QTGQGIFAFK CSRAEEIFNL LQELMQCNSI NVVEESMMMS
RSGHTPEMDM SRTPQTPNTP AFPIQAFPNG YPGYPIRGDS SQPSIADDHG HSLMGLEDQT
HTYVNTVSME GDLSMRHCVH SLPEVRPSTF PETTRGAMPV GGQGNPQSNL RCCPLEEHKD
PQVFLQTSSQ EVKFMLGPTP AQRHLLERER ERHGHNPHNL QPVEGAASSE TEGDEPSIGE
LTYENINGLR SGRKQRLSPS SVSQSVAHRR TALLNYENLP SLPPVWEYKE EEDFDEYEFS
EGPGTPNGYH QDGRGIHRDA LQNYVNTEQV QPPRLRHACP PHPRPCHPDR GGRIFSFDFR
RRSRSGVGGC EHSHMPPSRQ LNYIQVDLEG EPPCQALSSG GAQTQPQHQR LPPKKCGPQA
PRRSECYAVI DLKKTAAMSN LQKALPRDDG TSRKTRHNST DLPL
//
