ID A0A3P8QBT7_ASTCA Unreviewed; 597 AA.
AC A0A3P8QBT7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 2 {ECO:0000313|Ensembl:ENSACLP00000026592.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000026592.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000026592.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000026592.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3P8QBT7; -.
DR Ensembl; ENSACLT00000027216.1; ENSACLP00000026592.1; ENSACLG00000018069.1.
DR GeneTree; ENSGT00940000160376; -.
DR Proteomes; UP000265100; Chromosome 2.
DR Bgee; ENSACLG00000018069; Expressed in ovary and 5 other cell types or tissues.
DR CDD; cd12884; SPRY_hnRNP; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035778; SPRY_hnRNP_U.
DR PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR PANTHER; PTHR12381:SF66; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U-LIKE PROTEIN 2; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF02037; SAP; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00513; SAP; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 6..40
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 136..340
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 66..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..566
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 597 AA; 66260 MW; 20C0E06087BDA44F CRC64;
MKLADIKKLK VAELRSRLKE LGLDSRGLKA ELVERLWSAA EGEPSGGDGE EETLKLHDSS
PILLVQTEPA DVRPPSSEIG ATARHEVDRG YTDMATQTVA EPSPAAPQPD SEAAAAAGVT
ACPAEGGEQG HAEGPVEEDM GRGRSFYDMV KKPAPQRASG SVKIPHIYGS HLHFEVSPDG
SSGQPRFWAQ FPLLWSGCRL THGVQQGRVG FEVRLERKLL TAQPDDHEVR EPYGLRVGWS
VAVSSLLLGE DELSFCYDGR GKKVSDRKEE NFGEPFSEGD IIGCYAVNGA VELSFHKNGR
FVGVAFSTDT SVLRGRALFP HVLCKSCSFK LLLDPAAQPW YPGPPGFTPL ATLPPGQRVC
STSAPTSRAQ CEVVLMVGLP ASGKSVWARN YMKQHPEKQH RLLGTEELLA CMISGGQRDS
RLQQASHGLT EIIKMAAQTP GNYILDQCNI LFSALRHKLR LFTGFRRRVV VVFPSGDEWK
RRLSQHQMRD GEHIPETALL KLQVSCSLPE QQDDLLEELQ YVELPQEKAL KLLQEYKDEA
RRLLPPVPKH EKTRRLYRKR PHPHGPPSSH RTWSQPPRYV SANLAHFSLK AQLHLYY
//
