ID A0A3P8QFT5_ASTCA Unreviewed; 474 AA.
AC A0A3P8QFT5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Tubulin epsilon 1 {ECO:0000313|Ensembl:ENSACLP00000028121.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000028121.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000028121.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000028121.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tubulin family.
CC {ECO:0000256|ARBA:ARBA00009636, ECO:0000256|RuleBase:RU000352}.
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DR AlphaFoldDB; A0A3P8QFT5; -.
DR STRING; 8154.ENSACLP00000028121; -.
DR Ensembl; ENSACLT00000028781.1; ENSACLP00000028121.1; ENSACLG00000019080.1.
DR GeneTree; ENSGT00940000155723; -.
DR OMA; KRAHLHH; -.
DR OrthoDB; 5480452at2759; -.
DR Proteomes; UP000265100; Chromosome 15.
DR Bgee; ENSACLG00000019080; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR CDD; cd02190; epsilon_tubulin; 1.
DR Gene3D; 1.10.287.600; Helix hairpin bin; 1.
DR Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 1.
DR InterPro; IPR004057; Epsilon_tubulin.
DR InterPro; IPR008280; Tub_FtsZ_C.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR023123; Tubulin_C.
DR InterPro; IPR017975; Tubulin_CS.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; TUBULIN; 1.
DR PANTHER; PTHR11588:SF13; TUBULIN EPSILON CHAIN; 1.
DR Pfam; PF00091; Tubulin; 1.
DR Pfam; PF03953; Tubulin_C; 1.
DR PRINTS; PR01519; EPSLNTUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SMART; SM00865; Tubulin_C; 1.
DR SUPFAM; SSF55307; Tubulin C-terminal domain-like; 1.
DR SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
DR PROSITE; PS00227; TUBULIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000352};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU000352};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000352}.
FT DOMAIN 54..276
FT /note="Tubulin/FtsZ GTPase"
FT /evidence="ECO:0000259|SMART:SM00864"
FT DOMAIN 278..413
FT /note="Tubulin/FtsZ 2-layer sandwich"
FT /evidence="ECO:0000259|SMART:SM00865"
SQ SEQUENCE 474 AA; 52664 MW; 15D09609DBC6EF9C CRC64;
MTQSVVVQVG QCGNQVGCRF WDLALREHAH VNKRGLYDEA LNSFFRNVDS RKSDGAAFAV
GGRIQHLKAR AVLVDMEEGV VNQILQGPLR EVFDSTQLLT DVSGSGNNWA VGNMTYGSAY
REKIVDKLRK AAEQCDCLQC FFLIHSMGGG TGSGLGTRVL SLLEEEFPEV CRVVTSIYPS
GEDDVITSPY NSVLAMNKLT EHADCVLLVE NQSLVDIVNK IKVMSHGTKP GLNIKRNSAV
TSGQEGLSGA EKPFDAMNNI VANLLLNITS SARFEGSLNM DLNEIAMNLV PFPRLHYLVP
SLTPLYTLAD INVPTRRLDQ MFSDAFSKDH QLIQADPKHS LYLACALMVR GNVQVSDVRR
NIERLRPSLP FVSWNQEGWK TSLCSVPPVG HSHSLLALAN NTCVKPTFME LRERFTKLYR
KKAHLHHYLH VEGMEQSFFS EAIASLNSLI EEYHHLDATK ARLTPDAPRL SIAR
//
