ID A0A3P8QIX8_ASTCA Unreviewed; 414 AA.
AC A0A3P8QIX8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Major histocompatibility complex class I-related gene protein-like {ECO:0000313|Ensembl:ENSACLP00000029398.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000029398.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000029398.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000029398.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|RuleBase:RU004439}.
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DR AlphaFoldDB; A0A3P8QIX8; -.
DR Ensembl; ENSACLT00000030090.1; ENSACLP00000029398.1; ENSACLG00000019936.1.
DR GeneTree; ENSGT01100000263531; -.
DR Proteomes; UP000265100; Chromosome 22.
DR Bgee; ENSACLG00000019936; Expressed in spleen and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675:SF237; MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED; 1.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 346..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 242..316
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 374..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 414 AA; 47407 MW; DFD611DDB5FAFB5C CRC64;
MVTFLLVLHF SFSFFWTSER IKSVKGLDVY GHNVEDEERR KKMKAFIFFL LLGIQGAAAV
THSLKYFYTA SSQVPNFPEF VVVGMVDDVQ VDYYDSNTEK SVPKQDWFAS NIDQQYWESQ
TAKRRGDQQW FKANIEIAKQ RFNQTGGVHI YQRMCGCEWD EETGEVNGYH QEGYDGEDFI
SFDLKTATWV APKQQAVMTQ MKWGNNRAMM ALYKYYLTQI CPESLKKYVN YGRSSLMKTV
VPKVSLLQKS SSSPVSCHAT GFYPNRAEMV WKKDGVELHE GVNKGEILTN NDRTFQMSVD
LDLSSVKPED WHRYRCVFQL SGVNEDIATK LDKAVIKTNE GNSFSLIIPV VVAVVVLAAI
AVITFIIYKK RTEKRPPSPV ENREVKEQML PQAETTNSSA HKNMREDVSA RSSP
//
