ID A0A3P8QK26_ASTCA Unreviewed; 346 AA.
AC A0A3P8QK26;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Guanine nucleotide binding protein (G protein), alpha 14a {ECO:0000313|Ensembl:ENSACLP00000029412.1};
GN Name=GNA14 {ECO:0000313|Ensembl:ENSACLP00000029412.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000029412.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000029412.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000029412.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the G-alpha family. G(q) subfamily.
CC {ECO:0000256|ARBA:ARBA00007976}.
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DR AlphaFoldDB; A0A3P8QK26; -.
DR STRING; 8154.ENSACLP00000029412; -.
DR Ensembl; ENSACLT00000030106.1; ENSACLP00000029412.1; ENSACLG00000019930.1.
DR GeneTree; ENSGT00940000158510; -.
DR OMA; ENCMEES; -.
DR Proteomes; UP000265100; Chromosome 12.
DR Bgee; ENSACLG00000019930; Expressed in anal fin and 2 other cell types or tissues.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000654; Gprotein_alpha_Q.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF213; GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00442; GPROTEINAQ.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 346 AA; 40230 MW; 1AA8467DA64ED10F CRC64;
MAGCCVSAEE RENQRINEEI EKQLRRDKED SRMELKLLLL GTGESGKSTF IKQMRIIHGG
GYTDEDKRSY AKLVYQNIYT SMQTMVRAME ALGISFTDPQ NQSHASAVLE VEVDKVKDLD
SNLAMAVKSL WDDPGIQECY DRRREYQLSD STKYYLTDLD RISQPSYIPD LDDILRVRVP
TTGIIEYPFD MMVDVGGQRS ERRKWIHCFE NVTSIIFLVA LSEYDQVLAE CDNENRMEES
KALFKTIITY PWFQRSSVIL FLNKTDILKE KILYSHLSTY FPEFTGPQQD QVAAQKFILK
MYQEQDKDKT LYSHFTCATD TENIRLIFKD VKTAILRHNL GDFNLV
//
