ID   A0A3P8QVJ1_ASTCA        Unreviewed;       982 AA.
AC   A0A3P8QVJ1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000033563.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000033563.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000033563.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8QVJ1; -.
DR   STRING; 8154.ENSACLP00000033563; -.
DR   Ensembl; ENSACLT00000034362.1; ENSACLP00000033563.1; ENSACLG00000022731.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   OMA; NMLEDQM; -.
DR   Proteomes; UP000265100; Chromosome 3.
DR   Bgee; ENSACLG00000022731; Expressed in anal fin and 3 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 2.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          179..313
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          790..982
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   982 AA;  110819 MW;  359E678BB0B2EBDD CRC64;
     MKSLLVNVKG MLLENNIITF VKDELKKIQK VLSPDYPECF ESQREDERKQ SSREAFVKIT
     LDFLRRMKQE ELAECLCWMN QTFSNVLRDG PTFCHRNLKS ALRKKFQCVF EGIAKAGNPT
     LLNQIYTELY ITEGGTAEVN DEHEVRQIET ASRKTDRSET RIRQEDIFKS SPGRDEPIRT
     VLTRGVAGIG KTVLTQKYTL DWAEDKANQD IQFIFPFTFR ELNVLKEEKF SLVGLVHHFF
     TETKEAGICS FEDFQVVFIF DGLDECRLPL DFHKTTILTD PRKSTSVDVL LINLIRGKLL
     PSARLWITTR PAAASQIPPD CVDMVTEVRG FTDPQKEEYF RKRFRDEEQA SRIISHIKTS
     RSLHIMCHIP VFCWITATVL EDVLETREGG QLPKTLTEMY IHFLVVQAKV KKVKYDGGSE
     TDPHWSPESR KMIESLGKLA FDQLQEGNLI FYESDLTECG IDIRAASVYS GVFTQIFKEE
     RGLYQDKVFC FIHLSVQEFL AALHVHLTFI NSGLNLLEEQ QTASQKSETG ESAEKFYQSA
     VNKALQSPNG HLDLFLRFLL GLSLQTSQTL LRGLLTRIGS SSQTNQETVQ YIKNKLSENL
     SAEKSINLFH CLNELNDRSL VEEIQQSLRS GSLSTDKLSP AQWSALVFIL LSSEKDLDVF
     DLKKYSASEE ALLRLLPVVK ASNKAILSGC FLSKRSCEAL SSILSSQSCS LTELDLSNNN
     LQDSGVKLFN APLQSPHCTL ESLSLSGCLI TEEGCTSLAS ALSSNPSHLR ELDLSYNYPG
     DSIVKLLAAD DGSITAAGLC LFSPSDSCQL TIDTNTVNTK LQLSENNRKV ARVEEIQSYP
     DHPDRFDVYP QFLCRNGLTG RCYWEVEWRG NIYISVSYRQ IGRKGNSEDC LFGHNDQSWS
     LHCAGDGPRC VWQNKRYTSI SSSSSSSVSN RAAVYVDCPA GTLSFYRVAS DTLIHLHTFN
     TTFTQTLYPG FRFNPGSSVT LC
//