ID   A0A3P8QVK9_ASTCA        Unreviewed;       960 AA.
AC   A0A3P8QVK9;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000033583.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000033583.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000033583.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P8QVK9; -.
DR   Ensembl; ENSACLT00000034383.1; ENSACLP00000033583.1; ENSACLG00000022731.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   Proteomes; UP000265100; Chromosome 3.
DR   Bgee; ENSACLG00000022731; Expressed in anal fin and 3 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 4.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 4.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          99..233
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          768..960
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   960 AA;  107564 MW;  9A024276A20E39AA CRC64;
     MKQEELAECL QSICHRNLKS ALRKKFQCVF EGIAKAGNPT LLNQIYTELY ITEGGTAEVN
     DEHEVRQIET ASRKTDRSET RIRQEDIFKS SPGRDEPIRT VLTRGVAGIG KTVLTQKYTL
     DWAEDKANQD IQFIFPFTFR ELNVLKEEKF SLVGLVHHFF TETKEAGICS FEDFQVVFIF
     DGLDECRLPL DFHKTTILTD PRKSTSVDVL LINLIRGKLL PSARLWITTR PAAASQIPPD
     CVDMVTEVRG FTDPQKEEYF RKRFRDEEQA SRIISHIKTS RSLHIMCHIP VFCWITATVL
     EDVLETREGG QLPKTLTEMY IHFLVVQAKV KKVKYDGGSE TDPHWSPESR KMIESLGKLA
     FDQLQEGNLI FYESDLTECG IDIRAASVYS GVFTQIFKEE RGLYQDKVFC FIHLSVQEFL
     AALHVHLTFI NSGLNLLEEQ QTASQKSETG ESAEKFYQSA VNKALQSPNG HLDLFLRFLL
     GLSLQTSQTL LRGLLTRIGS SSQTNQETVQ YIKNKLSENL SAEKSINLFH CLNELNDRSL
     VEEIQQSLRS GSLSTDKLSP AQWSALVFIL LSSEKDLDVF DLKKYSASEE ALLRLLPVVK
     ASNKAILSGC FLSKRSCEAL SSILSSQSCS LTELDLSNNN LQDSGVKLFN APLQSPHCTL
     ESLRLNCCNL SGKSCEALSL VLSCPSSCLR ELDLSDNDLQ DSGAKYISAE LQSLHCTLKT
     LSLSGCLITE EGCTSLASAL SSNPSHLREL DLSYNYPGDS IVKLLAADDG SITAAGLCLF
     SPSDSCQLTI DTNTVNTKLQ LSENNRKVAR VEEIQSYPDH PDRFDVYPQF LCRNGLTGRC
     YWEVEWRGNI YISVSYRQIG RKGNSEDCLF GHNDQSWSLH CAGDGPRCVW QNKRYTSISS
     SSSSSVSNRA AVYVDCPAGT LSFYRVASDT LIHLHTFNTT FTQTLYPGFR FNPGSSVTLC
//