ID   A0A3P8QVL0_ASTCA        Unreviewed;       959 AA.
AC   A0A3P8QVL0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=General vesicular transport factor p115 {ECO:0000256|ARBA:ARBA00018243};
OS   Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX   NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000033715.1, ECO:0000313|Proteomes:UP000265100};
RN   [1] {ECO:0000313|Ensembl:ENSACLP00000033715.1, ECO:0000313|Proteomes:UP000265100}
RP   NUCLEOTIDE SEQUENCE.
RA   Datahose.;
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACLP00000033715.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the VDP/USO1/EDE1 family.
CC       {ECO:0000256|ARBA:ARBA00006960}.
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DR   AlphaFoldDB; A0A3P8QVL0; -.
DR   STRING; 8154.ENSACLP00000033715; -.
DR   Ensembl; ENSACLT00000034517.1; ENSACLP00000033715.1; ENSACLG00000022762.1.
DR   GeneTree; ENSGT00390000017018; -.
DR   OMA; LLDYEYC; -.
DR   OrthoDB; 1774at2759; -.
DR   Proteomes; UP000265100; Chromosome 6.
DR   Bgee; ENSACLG00000022762; Expressed in ovary and 8 other cell types or tissues.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR041209; P115_Arm_rpt.
DR   InterPro; IPR006955; Uso1_p115_C.
DR   InterPro; IPR006953; Vesicle_Uso1_P115_head.
DR   PANTHER; PTHR10013; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   PANTHER; PTHR10013:SF0; GENERAL VESICULAR TRANSPORT FACTOR P115; 1.
DR   Pfam; PF18770; Arm_vescicular; 1.
DR   Pfam; PF04871; Uso1_p115_C; 1.
DR   Pfam; PF04869; Uso1_p115_head; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          60..97
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   DOMAIN          350..637
FT                   /note="Vesicle tethering protein Uso1/P115-like head"
FT                   /evidence="ECO:0000259|Pfam:PF04869"
FT   DOMAIN          845..957
FT                   /note="Uso1/p115-like vesicle tethering protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04871"
FT   REGION          931..959
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          661..709
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          735..762
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        936..959
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   959 AA;  107167 MW;  4E10C87035A92868 CRC64;
     MNFFRGVISG QAAGPQPSGA ETIQKLCDRV ASSTLLEDRR DAVRALKSLS KKYRMEVGTQ
     AMDHLINILQ TDRSDSEILG YALDTLYNVI CNDEEEEQDE SEDENAQKQA DDLGLQFTDT
     FVQDPEHVTL LLTLLEEFDF HVRWPGVKLL TALLKNQGPQ IQGIILVSPM GVSRLMDLLA
     DSREVIRNDG LLLLQQLTKS NAAIQKIVAF ENAFERLLDI ITEEGSSDGG IVVEDCLLLL
     LNLLKNNSSN QNFFKEGSYI QRMKPWFEVG DDNSGWSAQK VTNLHLMLQL VRVMVSPVNS
     PGATASCQKS MFQCGLLQQL CTILMATGVP ADILTETINT VSEVIRGSQV NQDYFASVNA
     PSNPPRPAIV VLLMSMVNER QPFVLRCAVL YCFQCFLYKN QKGQGEIVAT LLPSTIDANS
     ISAGQLLCGG LFSADSLSNW CAAVALAHAL QDNLTQKEQL LRVQLATSLG KPPVSLLQQC
     TNILSQGDKI VRRGSKVQTR VGLLMLLCTW ISNCPIAVTH FLHNQENVPF LTAQISENLG
     EDERLVQGLC ALLLGICIYY NDNSLENYTK EKLKQLIEKR IGKENFVEKL CFITKHELYS
     RAAQKPQPVF PSPEQMLFDH EFTKLVKELE GVITKAVHKS SEEEKKEEEV KKTLEQHDNI
     VTQYKELIRE QDAQLQELKE QVACMTSQNE QLQATITQQQ SQILQHKDQY NILKLKLAKE
     NQGQSNSQGD GSQVNGLQTE ELTQLREEVE ELRKQHSLLQ TQLGDKDALI SSLKSGAAQT
     AEGPAGGSDD TELLQELEAL RSQVQSQSTE IGQLKMERQD LLRRAEVGCS DTLPSSDSSL
     DAAKMAELES RLGAQTSEME RLKAEVKNLS ESRAELEKRL DSTTSTVAIL QTEKEKLQTD
     VQESKKEQDD LLMLLADQDQ KITNLKKRLK ELGETVEDED DLDTRDQTDD DDEEDEDED
//