ID A0A3P8QVV7_ASTCA Unreviewed; 648 AA.
AC A0A3P8QVV7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Epsin-1-like {ECO:0000313|Ensembl:ENSACLP00000033201.1};
OS Astatotilapia calliptera (Eastern happy) (Chromis callipterus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Astatotilapia.
OX NCBI_TaxID=8154 {ECO:0000313|Ensembl:ENSACLP00000033201.1, ECO:0000313|Proteomes:UP000265100};
RN [1] {ECO:0000313|Ensembl:ENSACLP00000033201.1, ECO:0000313|Proteomes:UP000265100}
RP NUCLEOTIDE SEQUENCE.
RA Datahose.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACLP00000033201.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR AlphaFoldDB; A0A3P8QVV7; -.
DR STRING; 8154.ENSACLP00000033201; -.
DR Ensembl; ENSACLT00000033987.1; ENSACLP00000033201.1; ENSACLG00000022498.1.
DR GeneTree; ENSGT00940000160411; -.
DR OMA; NPWGQPQ; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000265100; Chromosome 11.
DR Bgee; ENSACLG00000022498; Expressed in liver and 8 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276:SF48; EPSIN-1; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 3.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 2.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121}.
FT DOMAIN 12..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 148..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..377
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 67249 MW; 98C10D3002C151D8 CRC64;
MSTSSLRRQV KNIVHNYSEA EIKVREATSN DPWGPSSSLM SEIADLTYNV VAFSEIMSMV
WKRLNDHGKN WRHVYKAMTL MEYLIKTGSE RVAQQCRENI YAVQTLKDFQ YIDRDGKDQG
VNVREKAKQL VTLLKDEERL REERIHALKT KEKMAQTSSA SSAPSAPSLG GSLSLGSHSG
GADSEQAWPQ SSGEEDLQLQ LALAMSKEEA EQNSTDPLED AELRYALTLS KEIHQQEERL
RRGDDLRLQM AIEESKREKP KPEESALMEL SAVDPWGTPA APVVSSAGPS PLPTVSASAA
SGPWGTATTD PWGVASPTSP TSSDPWGGGA PPVIAPPPDP WGESSNKVNN VDPWGSSAVT
PPSADPWGPP LPPSTSSSGG PVDPWAKDGP VPASDPITSD IWSGSAKHTN GTGDPEQLGS
SGAGADSTGS PVPFDLSSLG SSLPVRKTPE SFLGPNAALV DLDSLVPSKP KPKQPPPPSI
SSSSAHNPFL QNTGSSPATG MAVTPGSTIS SRGVSPTPAS SNPFGVAPPM TSISPQPSSL
GLSGLRTSPV PPNPMLGMVQ PGMGMVPMSM GMGAPGMGLG MMQPSPMSMP YSGLSPMAPP
GSGLMGTGVA PPPQLILGGP TGPGGVMGAG GSVGGGGTTG TSTNPFLL
//
